{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:03:54Z","timestamp":1787756634716,"version":"build-2784847793"},"reference-count":57,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,11,17]],"date-time":"2017-11-17T00:00:00Z","timestamp":1510876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to analyze linear and volumetric hard tissue changes in severely resorbed alveolar sockets after ridge augmentation procedure and to compare them with spontaneous healing using three\u2010dimensional cone beam computed tomography (<jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Thirty patients (mean age 53.2\u00a0\u00b1\u00a06.3\u00a0years) requiring tooth extraction for advanced periodontitis were randomly allocated to test and control groups. The test sites were grafted using a collagenated bovine\u2010derived bone (<jats:styled-content style=\"fixed-case\">DBBM<\/jats:styled-content>\u2010C) covered with a collagen membrane, while control sites had spontaneous healing. Both groups healed by secondary intention. Linear and volumetric measurements were taken on superimposed <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> images obtained after tooth extraction and 12\u00a0months later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Greater horizontal shrinkage, localized mainly in the crestal zone, was observed in the control group (4.92\u00a0\u00b1\u00a02.45\u00a0mm) compared to the test group (2.60\u00a0\u00b1\u00a01.24\u00a0mm). While both groups presented a rebuilding of the buccal wall, it was most pronounced in the grafted sockets (2.50\u00a0\u00b1\u00a02.12\u00a0mm vs. 0.51\u00a0\u00b1\u00a01.02\u00a0mm). A significant difference was also registered in the percentage of volume loss between grafted and non\u2010grafted sites (9.14% vs. 35.16%, <jats:italic>p<\/jats:italic>\u2010value &lt;.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Alveolar sockets with extensive buccal bone deficiencies undergo significant three\u2010dimensional volumetric alterations following natural healing. The immediate application of a slow\u2010resorbing xenograft with a covering collagen membrane seems to be effective in improving alveolar ridge shape and dimensions, thus potentially reducing the need for adjunctive regenerative procedures at the time of implant placement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.13099","type":"journal-article","created":{"date-parts":[[2017,11,17]],"date-time":"2017-11-17T13:02:39Z","timestamp":1510923759000},"page":"202-214","source":"Crossref","is-referenced-by-count":49,"title":["Three\u2010dimensional analysis of bone remodeling following ridge augmentation of compromised extraction sockets in periodontitis patients: A randomized controlled study"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0657-0787","authenticated-orcid":false,"given":"Mario","family":"Aimetti","sequence":"first","affiliation":[{"name":"Department of Surgical Sciences C.I.R. 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