{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:59:06Z","timestamp":1760889546180,"version":"3.37.3"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,1,18]],"date-time":"2018-01-18T00:00:00Z","timestamp":1516233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study of a human autopsy case aimed to characterize the histologic and micro\u2010computed tomographic results of maxillary sinus augmentation using a synthetic bone substitute and simultaneous implant placement at 6\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>This report is based on the whole\u2010body donation of a 62\u2010year\u2010old male patient who died due to bladder cancer. Implants had been placed in conjunction with sinus augmentation using a mixture of biphasic calcium phosphate and autogenous bone into both maxillary sinuses 6\u00a0years prior to the body donation. The maxillary sinus areas containing implants were gently removed from the cadaver and scanned using high\u2010resolution micro\u2010computed tomography. Samples were sectioned, prepared for undecalcified histologic slides and stained with haematoxylin\u2010eosin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The augmented volume was observed up to the apex of the implants, which were successfully osseointegrated. Cross\u2010sectional micro\u2010computed tomographic views revealed that the bone\u2010substitute particles were embedded in radiopaque\u2010mineralized tissues showing a trabecular pattern around the implants. The histologic analysis revealed mature lamellar bone surrounding the remaining bone\u2010substitute particles as well as well\u2010organized bone marrow spaces in the augment bone area and around the dental implants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This human autopsy study histologically confirmed the presence of successful bone formation and long\u2010term volume stability after sinus augmentation using biphasic calcium phosphate and simultaneous implant placement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.13124","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T04:14:48Z","timestamp":1516335288000},"page":"339-345","source":"Crossref","is-referenced-by-count":8,"title":["Report of a human autopsy case in maxillary sinuses augmented using a synthetic bone substitute: Micro\u2010computed tomographic and histologic observations"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1276-5978","authenticated-orcid":false,"given":"Jung\u2010Seok","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Periodontology Research Institute for Periodontal Regeneration College of Dentistry Yonsei University  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6906-7209","authenticated-orcid":false,"given":"Jae\u2010Kook","family":"Cha","sequence":"additional","affiliation":[{"name":"Department of Periodontology Research Institute for Periodontal Regeneration College of Dentistry Yonsei University  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1764-7447","authenticated-orcid":false,"given":"Daniel S.","family":"Thoma","sequence":"additional","affiliation":[{"name":"Department of Fixed and Removable Prosthodontics and Dental Material Science Dental School University of Zurich  Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6371-4172","authenticated-orcid":false,"given":"Ui\u2010Won","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Periodontology Research Institute for Periodontal Regeneration College of Dentistry Yonsei University  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40729-017-0099-x"},{"key":"e_1_2_6_3_1","first-page":"613","article-title":"Grafting of the maxillary sinus floor with autogenous marrow and bone","volume":"38","author":"Boyne P. J.","year":"1980","journal-title":"Journal of Oral Surgery"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.5051\/jpis.2011.41.2.98"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01821.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01708.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2013.08.003"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12901"},{"key":"e_1_2_6_9_1","first-page":"218","article-title":"Bone augmentation procedures in localized defects in the alveolar ridge: Clinical results with different bone grafts and bone\u2010substitute materials","volume":"24","author":"Jensen S. S.","year":"2009","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.5051\/jpis.2010.40.2.76"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12471"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12086"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2013.08.008"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.5051\/jpis.2016.46.1.57"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.3709"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.2667"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12008"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.3422"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12551"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12043"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02546.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2015.01.039"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.3472"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fclr.13124","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.13124","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T13:05:15Z","timestamp":1695647115000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/clr.13124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,18]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1111\/clr.13124"],"URL":"https:\/\/doi.org\/10.1111\/clr.13124","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"type":"print","value":"0905-7161"},{"type":"electronic","value":"1600-0501"}],"subject":[],"published":{"date-parts":[[2018,1,18]]}}}