{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T06:33:31Z","timestamp":1773902011843,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,5,12]],"date-time":"2018-05-12T00:00:00Z","timestamp":1526083200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["NRF\u20102017R1A2B2002537"],"award-info":[{"award-number":["NRF\u20102017R1A2B2002537"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007619","name":"Osteology Foundation","doi-asserted-by":"publisher","award":["16\u2010004"],"award-info":[{"award-number":["16\u2010004"]}],"id":[{"id":"10.13039\/501100007619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this experimental in vivo investigation was to assess the anti\u2010resorptive effect of low concentration pamidronate on the buccal plate in fresh extraction sockets.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>The distal roots of the third premolars were extracted bilaterally in six dogs. A collagen matrix loaded with either pamidronate (test group) or saline (control group) was positioned on the outer surface of buccal bone immediately after tooth extraction and subsequently covered with a coronally advanced flap. Histological and histomorphometric outcomes were evaluated 12\u00a0weeks later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean vertical distance between the buccal and lingual bone crest differed significantly between the test and control groups (0.52\u00a0\u00b1\u00a00.43 and 2.21\u00a0\u00b1\u00a01.15\u00a0mm, respectively; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.037). The width of the buccal bone 1\u00a0mm below the crest was significantly wider in the test group than the control group (4.68\u00a0\u00b1\u00a00.68 vs. 3.44\u00a0\u00b1\u00a00.60\u00a0mm, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Local application of pamidronate onto a collagen matrix may reduce the dimensional changes of the buccal bone plate both vertically and horizontally.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.13260","type":"journal-article","created":{"date-parts":[[2018,5,12]],"date-time":"2018-05-12T07:21:21Z","timestamp":1526109681000},"page":"688-696","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Anti\u2010resorptive effect of pamidronate on extraction socket wall in dogs"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6906-7209","authenticated-orcid":false,"given":"Jae\u2010Kook","family":"Cha","sequence":"first","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry Yonsei University Seoul South Korea"},{"name":"Department of Periodontology, Faculty of Odontology Complutense University of Madrid Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoo\u2010Kyung","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry Yonsei University Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myong Ji","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry Yonsei University Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariano","family":"Sanz","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Faculty of Odontology Complutense University of Madrid Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6371-4172","authenticated-orcid":false,"given":"Ui\u2010Won","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry Yonsei University Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,5,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1006\/ijom.2002.0472"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00642.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1988.tb02129.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-014-0633-9"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12074"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12447"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01575.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12483"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr414"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12041"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2006.00923.x"},{"key":"e_1_2_7_13_1","unstructured":"Jack DeRuiter R. 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