{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T10:42:15Z","timestamp":1769078535745,"version":"3.49.0"},"reference-count":3,"publisher":"Wiley","issue":"S18","license":[{"start":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T00:00:00Z","timestamp":1539129600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The task of this working group was to update the knowledge about the use of drugs and biologicals affecting healing of soft tissue and bone during implant treatment or procedures associated with it. Moreover, the impact of titanium particles and biocorrosion on complications and implant survival has been analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The literature in the areas of interest (platelet concentrates, antiresorptive drugs as well as implant\u2013host interaction) was screened using systematic reviews for the former two areas, whereas a narrative critical review was performed for the latter topic. Two manuscripts on platelet concentrates, one manuscript on antiresorptive drugs and one manuscript on the effects of biocorrosion, were presented for group analysis with subsequent discussion in the plenum and final consensus approval.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Results and conclusions of the individual reviews of the three topics are presented in the respective papers. Conclusions of the group on strengths and weaknesses of available evidence as well as consensus statements and directions for further research are provided in this study.<\/jats:p><jats:p>The following papers were subject to group discussions and formed the basis for the consensus statements:<\/jats:p><jats:p>\n<jats:list list-type=\"simple\">\n\n<jats:list-item><jats:p>St\u00e4hli A, Strauss FJ, Gruber R. (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"#clr13270-bib-0001\"\/>) The use of platelet\u2010rich\u2010plasma to enhance the outcomes of implant\u2010related therapies: a systematic review<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Strauss FJ, St\u00e4hli A, Gruber R. (2018) The use of platelet\u2010rich\u2010fibrin to enhance the outcomes of implant\u2010related therapies: a systematic review<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Mombelli A, Hashim D, Cionca N. (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"#clr13270-bib-0003\"\/>) What is the impact of titanium particles and bio\u2010corrosion on implant survival and complications? A critical review<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Stavropoulos A, Bertl K, Pietschmann P, Pandis N, Morten Schi\u00f8dt, Klinge B. (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"#clr13270-bib-0004\"\/>) The effect of antiresorptive drugs on implant therapy: a systematic review.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.13270","type":"journal-article","created":{"date-parts":[[2018,10,11]],"date-time":"2018-10-11T05:37:16Z","timestamp":1539236236000},"page":"93-99","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Drugs and diseases: Summary and consensus statements of group 1. The 5<sup>th<\/sup><scp>EAO<\/scp> Consensus Conference 2018"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2008-7188","authenticated-orcid":false,"given":"Henning","family":"Schliephake","sequence":"first","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery University Medicine George\u2010Augusta\u2010University G\u00f6ttingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1197-599X","authenticated-orcid":false,"given":"Alberto","family":"Sicilia","sequence":"additional","affiliation":[{"name":"Section of Periodontology Faculty of Medicine and Health Science University Clinic of Dentistry University of Oviedo Oviedo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilal Al","family":"Nawas","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Medical Centre of the Johannes Gutenberg University Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikos","family":"Donos","sequence":"additional","affiliation":[{"name":"Lead Centre for Immunobiology &amp; Regenerative Medicine QMUL Barts and The London School of Medicine &amp; Dentistry London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5400-9009","authenticated-orcid":false,"given":"Reinhard","family":"Gruber","sequence":"additional","affiliation":[{"name":"Department of Oral Biology Medical University of Vienna, MedUni Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f8ren","family":"Jepsen","sequence":"additional","affiliation":[{"name":"Department of Periodontology University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iva","family":"Milinkovic","sequence":"additional","affiliation":[{"name":"Department of Periodontology School of Dental Medicine University of Belgrade Beograd Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Mombelli","sequence":"additional","affiliation":[{"name":"Division of Periodontology University Clinics of Dental Medicine University of Geneva Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Manuel","family":"Navarro","sequence":"additional","affiliation":[{"name":"Private Practice Harley Street London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Quirynen","sequence":"additional","affiliation":[{"name":"Department of Dentistry Universitair Ziekenhuis Leuven Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella","family":"Rocchietta","sequence":"additional","affiliation":[{"name":"The London Centre for Implant and Aesthetic Dentistry (LCIAD) Ltd London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morten","family":"Schi\u00f8dt","sequence":"additional","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f8ren","family":"Schou","sequence":"additional","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery School of Dentistry University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"St\u00e4hli","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Parodontologie Zahnmedizinische Kliniken Bern Universit\u00e4t Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Stavropoulos","sequence":"additional","affiliation":[{"name":"Department of Periodontology Centre of Oral Health Sciences Faculty of Odontology Malm\u00f6 University Malm\u00f6 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Miguel","family":"S\u00e1nchez Su\u00e1rez","sequence":"additional","affiliation":[{"name":"Private Practice Group Aula Dental Avanzada Avd de las Salinas 49, San Pedro del Pinatar Murcia 30740 Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,10]]},"reference":[{"issue":"18","key":"e_1_2_4_2_1","first-page":"6","article-title":"The use of platelet\u2010rich\u2010plasma to enhance the outcomes of implant\u2010related therapies: A systematic review","volume":"29","author":"St\u00e4hli A.","year":"2018","journal-title":"Clinical Oral Implants Research"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13305"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13282"}],"updated-by":[{"DOI":"10.1111\/clr.13561","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T00:00:00Z","timestamp":1580947200000}}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fclr.13270","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.13270","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T09:30:29Z","timestamp":1693215029000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/clr.13270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":3,"journal-issue":{"issue":"S18","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1111\/clr.13270"],"URL":"https:\/\/doi.org\/10.1111\/clr.13270","archive":["Portico"],"relation":{"correction":[{"id-type":"doi","id":"10.1111\/clr.13561","asserted-by":"object"}]},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"2018-04-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}