{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T21:13:15Z","timestamp":1764364395923,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,5,12]],"date-time":"2019-05-12T00:00:00Z","timestamp":1557619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To histologically and radiographically evaluate soft (primary outcome) and hard tissue integration of two\u2010piece titanium and zirconia dental implants with\/without buccal dehiscence defects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials &amp; methods<\/jats:title><jats:p>In six dogs, five implants were randomly placed on both sides of the mandible: (a) Z1: a zirconia implant (modified surface) within the bony housing, (b) Z2: a zirconia implant (standard surface) within the bony housing, (c) T: a titanium implant within the bony housing, (d) Z1_D: a Z1 implant placed with a buccal bone dehiscence (3\u00a0mm in height, identical width to implant body), and (e) T_D: a titanium implant placed with a buccal bone dehiscence. Two weeks of healing and 6\u00a0months of loading were applied on each hemi\u2010mandible, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median level of the margo mucosae shifted more apically over time in all groups (borderline statistical significance in groups Z1_D: \u22120.52\u00a0mm and T_D: \u22121.26\u00a0mm). The median height of the peri\u2010implant mucosa in groups Z1_D and T_D was greatest at 2\u00a0weeks and 6\u00a0months, but the linear change in the peri\u2010implant mucosa was statistically significant only for group T_D over time (\u22121.45\u00a0mm). Z1 demonstrated a higher bone\u2010to\u2010implant contact compared to Z2 and T. Minimal change of radiographic marginal bone levels in all groups was observed (&lt;1\u00a0mm).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>When buccal dehiscence was presented, titanium implants presented significant loss of peri\u2010implant mucosal height compared to zirconia implants with a modified surface, due to greater apical shift of the margo mucosae. A modified zirconia surface enhanced osseointegration.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.13451","type":"journal-article","created":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T03:16:58Z","timestamp":1556680618000},"page":"660-669","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Tissue integration of zirconia and titanium implants with and without buccal dehiscence defects\u2014A histologic and radiographic preclinical study"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1764-7447","authenticated-orcid":false,"given":"Daniel S.","family":"Thoma","sequence":"first","affiliation":[{"name":"Clinic for Fixed and Removable Prosthodontics and Dental Material Science University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7695-1708","authenticated-orcid":false,"given":"Hyun\u2010Chang","family":"Lim","sequence":"additional","affiliation":[{"name":"Clinic for Fixed and Removable Prosthodontics and Dental Material Science University of Zurich Zurich Switzerland"},{"name":"Department of Periodontology, School of Dentistry Kyung Hee University Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyeong\u2010Won","family":"Paeng","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration Yonsei University College of Dentistry Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6371-4172","authenticated-orcid":false,"given":"Ui\u2010Won","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration Yonsei University College of Dentistry Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8280-7347","authenticated-orcid":false,"given":"Christoph H. 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