{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:22:50Z","timestamp":1790922170439,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T00:00:00Z","timestamp":1600819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/aim<\/jats:title><jats:p>This study evaluated marginal soft tissue recession at implants with simultaneous lateral guided bone regeneration (GBR), at least five years after prosthetic loading.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Patients treated with GBR at the time of implant placement and adherent to supportive periodontal therapy (SPT) program with at least 5\u00a0years of follow\u2010up were re\u2010examined in 5 clinical centers. At the last follow\u2010up, clinical and radiographic data on peri\u2010implant hard and soft tissue were collected. Multilevel analysis considering center, patient, and implant (brand, length, diameter, position) was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 96 patients and 195 augmented implants were included. The mean duration of SPT was 8.3\u00a0\u00b1\u00a03.1\u00a0years, while mean recall frequency was 4.5\u00a0\u00b1\u00a01.3\u00a0months. Sixty\u2010five (33%) implants received soft tissue graft before prosthetic delivery. Twenty\u2010one (11%) implants developed biological complications during the follow\u2010up. No implant failure was reported. Mean difference in bone levels (\u0394BL) was \u22120.7\u00a0\u00b1\u00a00.9\u00a0mm, while mean difference in keratinized tissue (\u0394KT) was \u22120.4\u00a0\u00b1\u00a00.9\u00a0mm. Eighty\u2010five (44%) implants showed recession (REC) of soft tissue margin (mean 0.6\u00a0\u00b1\u00a00.8\u00a0mm). The presence of REC was associated with use of non\u2010resorbable membrane (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.0001) and wider implant diameter (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.0305), while use of soft tissue graft significantly predicted higher stability of peri\u2010implant mucosal margin (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.0003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Peri\u2010implant mucosal recession is a common feature 5\u00a0years after lateral GBR. The risk of recession may be reduced using GBR with resorbable membranes, small diameter implants, and soft tissue grafting before prosthetic treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.13658","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T10:43:10Z","timestamp":1599043390000},"page":"1116-1124","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Marginal soft tissue recession after lateral guided bone regeneration at implant site: A long\u2010term study with at least 5 years of loading"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3781-1715","authenticated-orcid":false,"given":"Francesco","family":"Cairo","sequence":"first","affiliation":[{"name":"Research Unit in Periodontology and Periodontal Medicine, Department of Clinical and Experimental Medicine University of Florence Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Nieri","sequence":"additional","affiliation":[{"name":"Research Unit in Periodontology and Periodontal Medicine, Department of Clinical and Experimental Medicine University of Florence Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Cavalcanti","sequence":"additional","affiliation":[{"name":"Private Practice Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Landi","sequence":"additional","affiliation":[{"name":"Private Practice Roma\u2010Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Rupe","sequence":"additional","affiliation":[{"name":"Private Practice Benevento Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola Marco","family":"Sforza","sequence":"additional","affiliation":[{"name":"Private Practice Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Pace","sequence":"additional","affiliation":[{"name":"Research Unit in Periodontology and Periodontal Medicine, Department of Clinical and Experimental Medicine University of Florence Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Barbato","sequence":"additional","affiliation":[{"name":"Research Unit in Periodontology and Periodontal Medicine, Department of Clinical and Experimental Medicine University of Florence Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.3910"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12665"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12786"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12039"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12957"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12593"},{"issue":"4","key":"e_1_2_8_8_1","first-page":"387","article-title":"Patient satisfaction and aesthetic outcome of implant\u2010supported single\u2010tooth replacements performed by dental students: A retrospective evaluation 8 to 12 years after treatment","volume":"6","author":"Bonde M. J.","year":"2013","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12861"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12750"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01266.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01388.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01781.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.01001.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12953"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13540"},{"issue":"1","key":"e_1_2_8_17_1","first-page":"28","article-title":"Soft tissue stability related to mucosal recession at dental implants: A systematic review","volume":"51","author":"Iorio\u2010Siciliano V.","year":"2020","journal-title":"Quintessence International"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.11607\/ijp.5883"},{"key":"e_1_2_8_19_1","first-page":"71","volume-title":"Sample size for clinical trials","author":"Julious S. A.","year":"2010"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02522.x"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12806"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12635"},{"issue":"1","key":"e_1_2_8_23_1","first-page":"11","article-title":"Bone augmentation at implant dehiscences and fenestrations. A systematic review of randomised controlled trials","volume":"9","author":"Merli M.","year":"2016","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13052"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02474.x"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12278"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13126"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02214.x"},{"issue":"4","key":"e_1_2_8_29_1","first-page":"527","article-title":"Gingival recession around implants: A 1\u2010year longitudinal prospective study","volume":"15","author":"Small P. N.","year":"2000","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13050"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-8-200710160-00010-w1"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.13658","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/clr.13658","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.13658","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T17:47:22Z","timestamp":1693763242000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/clr.13658"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,23]]},"references-count":30,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1111\/clr.13658"],"URL":"https:\/\/doi.org\/10.1111\/clr.13658","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,23]]},"assertion":[{"value":"2020-03-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}