{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T12:06:36Z","timestamp":1774699596463,"version":"3.50.1"},"reference-count":66,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T00:00:00Z","timestamp":1611532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Evaluate the effects of two different machined\u2010collar lengths and designs on peri\u2010implant healing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>An implant with a microtextured surface and 3.6mm\u2010long internal\u2010connection machined collar was compared to two implants that had an identical 1.2mm\u2010long external\u2010connection machined collar, but one had the microtextured surface while the other's was machined. Participants received the three implants, with microgap at the crest, alternately at five sites between mental foramen, and a full\u2010arch prosthesis. Peri\u2010implant bone levels were measured after 23 to 26\u00a0years of function. Keratinized tissue height, plaque, probing depth, bleeding, and purulence were also evaluated. Descriptive and mixed models for repeated\\measures analyses were used, with Bonferroni correction for pairwise comparisons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010two participants (110 implants) were evaluated at the 25\u2010year examination. Microtextured implants with the longer machined collar had significantly greater mean marginal bone loss (\u22121.77mm\u00a0\u00b1\u00a00.18, mean\u00a0\u00b1\u00a0SE) than machined (\u22120.85mm\u00a0\u00b1\u00a00.18, <jats:italic>p &lt; .001<\/jats:italic>) and microtextured (\u22121.00\u00a0\u00b1\u00a00.18mm, <jats:italic>p &lt;<\/jats:italic> .<jats:italic>001<\/jats:italic>) implants with the shorter machined collar. Keratinized tissue height was greater for internal\u2010connection (0.74mm\u00a0\u00b1\u00a00.10) versus external\u2010connection (0.51\u00a0\u00b1\u00a00.08, <jats:italic>p\u00a0=\u00a0 0.01<\/jats:italic>) microtextured implants. No differences were observed for plaque (<jats:italic>p\u00a0=\u00a00.78<\/jats:italic>), probing depth (<jats:italic>p\u00a0=\u00a00.42<\/jats:italic>), bleeding (<jats:italic>p<\/jats:italic>\u00a0 = <jats:italic>0.07<\/jats:italic>), and purulence (<jats:italic>p<\/jats:italic>\u00a0=\u00a0<jats:italic>1.00<\/jats:italic>). Implant survival rate was 99%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Implants with the 1.2mm machined collar limited bone loss to 1mm, while those with the longer machined collar showed\u00a0&gt;\u00a01.5mm loss after 25\u00a0years of function with microgap at the crest. Internal\u2010connection design and fixture surface microtexturing did not result in greater bone preservation.<\/jats:p><jats:p>ClinicalTrials.gov Identifier: NCT03862482.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.13699","type":"journal-article","created":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T12:30:28Z","timestamp":1607949028000},"page":"285-296","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Prospective randomized clinical trial evaluating the effects of two different implant collar designs on peri\u2010implant healing and functional osseointegration after 25 years"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0507-7117","authenticated-orcid":false,"given":"Aldo Joseph","family":"Camarda","sequence":"first","affiliation":[{"name":"D\u00e9partement de stomatologie Faculty of Dental Medicine Universit\u00e9 de Montr\u00e9al Pavillion Roger\u2010Gaudry Montreal QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Durand","sequence":"additional","affiliation":[{"name":"D\u00e9partement de sant\u00e9 buccale Faculty of Dental Medicine Universit\u00e9 de Montr\u00e9al Montreal QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marwa","family":"Benkarim","sequence":"additional","affiliation":[{"name":"Faculty of Dental Medicine Universit\u00e9 de Montr\u00e9al Montreal QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre H.","family":"Rompr\u00e9","sequence":"additional","affiliation":[{"name":"Faculty of Dental Medicine Universit\u00e9 de Montr\u00e9al Montreal QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevi\u00e8ve","family":"Guertin","sequence":"additional","affiliation":[{"name":"D\u00e9partement de dentisterie de restauration Faculty of Dental Medicine Universit\u00e9 de Montr\u00e9al Montreal QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo","family":"Ciaburro","sequence":"additional","affiliation":[{"name":"D\u00e9partement de dentisterie de restauration Faculty of Dental Medicine Universit\u00e9 de Montr\u00e9al Montreal QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,25]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"175","volume-title":"Tissue\u2010integrated prostheses: Osseointegration in clinical dentistry","author":"Adell R.","year":"1987"},{"key":"e_1_2_9_3_1","first-page":"155","article-title":"Osseointegrated titanium implants. Requirements for insuring a long\u2010lasting, direct bone\u2010to\u2010implant anchorage","volume":"52","author":"Albrektsson T.","year":"1981","journal-title":"Acta Scandinavia"},{"key":"e_1_2_9_4_1","first-page":"11","article-title":"The long\u2010term efficacy of currently used dental implants: A review and proposed criteria of success","volume":"1","author":"Albrektsson T.","year":"1986","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1994.050303.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2004.01028.x"},{"key":"e_1_2_9_7_1","first-page":"31","article-title":"Clinical and microbiological findings that may contribute to dental implant failure","volume":"5","author":"Becker W.","year":"1990","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00747.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12957"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2005.00998.x"},{"key":"e_1_2_9_11_1","first-page":"168","article-title":"Surface analysis of an original Br\u00e5nemark implant and three related clones","volume":"7","author":"Binon P. P.","year":"1992","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"e_1_2_9_13_1","first-page":"302","article-title":"Optimization of surface micromorphology for enhanced osteoblast responses in vitro","volume":"7","author":"Bowers K. T.","year":"1992","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3913(83)80101-2"},{"key":"e_1_2_9_15_1","first-page":"11","volume-title":"Tissue\u2010integrated prostheses: Osseointegration in clinical dentistry","author":"Br\u00e5nemark P.\u2010I.","year":"1987"},{"key":"e_1_2_9_16_1","first-page":"231","article-title":"The effects of implant surface topography on the behaviour of cells","volume":"3","author":"Brunette D. M.","year":"1998","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_17_1","volume-title":"Nonparametric analysis of longitudinal data in factorial experiments","author":"Brunner E.","year":"2002"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/08959374990130012301"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820250708"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.1.115"},{"issue":"9","key":"e_1_2_9_21_1","first-page":"733","article-title":"Long\u2010term randomized clinical trial evaluating the effects of fixture surface acid\u2010etching and machined collar design on bone healing","volume":"49","author":"Camarda A. J.","year":"2018","journal-title":"Quintessence International"},{"key":"e_1_2_9_22_1","first-page":"21","article-title":"Removal torques for polished and rough titanium implants","volume":"3","author":"Carlsson L.","year":"1988","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"issue":"2","key":"e_1_2_9_23_1","first-page":"101","article-title":"Maximum occlusal force levels in patients with osseointegrated oral implant prostheses and patients with complete dentures","volume":"2","author":"Carr A. B.","year":"1987","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.2.186"},{"key":"e_1_2_9_25_1","first-page":"289","article-title":"Attachment and growth of periodontal cells on smooth and rough titanium","author":"Cochran D. L.","year":"1994","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_26_1","first-page":"91","article-title":"The longitudinal clinical efficacy of osseointegrated dental implants: A 3\u2010year report","volume":"2","author":"Cox J. F.","year":"1987","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1992.030106.x"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007840050085"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20140007"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070204.x"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.050342"},{"key":"e_1_2_9_32_1","first-page":"422","article-title":"Comparative surface analysis and clinical performance studies of Br\u00e5nemark implants and related clones","volume":"9","author":"Helsingen A. L.","year":"1994","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.9.1412"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.11.1117"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.10.1372"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01360.x"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01626.x"},{"issue":"4","key":"e_1_2_9_38_1","first-page":"527","article-title":"Microbial leakage and marginal fit of the implant\u2010abutment interface","volume":"12","author":"Jansen V. K.","year":"1997","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_39_1","first-page":"289","article-title":"Determination of micromotion at the implant bone interface \u2013 an in vitro methodologic study","volume":"5","author":"Karl M.","year":"2015","journal-title":"Dentistry"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.18314\/jdms.v1i1.1242"},{"key":"e_1_2_9_41_1","first-page":"155","article-title":"Surface roughness modulates the local production of growth factors and cytokines by osteoblast\u2010like MG\u201063 cells","volume":"32","author":"Kieswetter K.","year":"1996","journal-title":"Journal of Biomedical Research"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.30328"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1997.080601.x"},{"key":"e_1_2_9_44_1","first-page":"199","volume-title":"Tissue\u2010integrated prostheses: Osseointegration in clinical dentistry","author":"Lekholm U.","year":"1987"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11517-018-1937-6"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2010.01.003"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12311"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.03.004"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1987.tb00298.x"},{"key":"e_1_2_9_50_1","unstructured":"Niznick G. A.(1989).Open letters no. 1 and no. 2 to the dental profession Core\u2010Vent Corporation Newsletter and manufacturer\u2019s product description. Encino California USA."},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1997.080407.x"},{"key":"e_1_2_9_52_1","first-page":"80","volume-title":"Proceedings of the Second International Congress on Tissue Integration","author":"Quirynen M.","year":"1992"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1993.040307.x"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02524.x"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00907.x"},{"key":"e_1_2_9_56_1","first-page":"15","article-title":"The reactions of bone, connective tissue, and epithelium to endosteal implants with titanium\u2010sprayed surfaces","volume":"9","author":"Schroeder A.","year":"1981","journal-title":"Journal of Oral and Maxillofacial Surgery"},{"issue":"5","key":"e_1_2_9_57_1","first-page":"409","article-title":"The new restorative concept of the ITI dental implant system design and engineering","volume":"13","author":"Sutter F.","year":"1993","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4636(199822)43:2<192::AID-JBM14>3.0.CO;2-K"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2010.01982.x"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820190802"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070102.x"},{"issue":"3","key":"e_1_2_9_62_1","first-page":"540","article-title":"Influence of microgap location and configuration on peri\u2010implant bone morphology in non\u2010submerged implants: An experimental study in dogs","volume":"25","author":"Weng D.","year":"2010","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"issue":"6","key":"e_1_2_9_63_1","first-page":"622","article-title":"Design and surface characteristics of 13 commercially available oral implant systems","volume":"8","author":"Wennerberg A.","year":"1993","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"issue":"1","key":"e_1_2_9_64_1","first-page":"38","article-title":"Bone tissue response to commercially pure titanium implants blasted with fine and coarse particles of aluminum oxide","volume":"11","author":"Wennerberg A.","year":"1996","journal-title":"The International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_9_65_1","first-page":"309","volume-title":"Advances in Biomaterials","author":"Wilke H. J.","year":"1990"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1563\/AAID-JOI-D-11-00221"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/265412"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.13699","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/clr.13699","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.13699","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T01:28:16Z","timestamp":1693704496000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/clr.13699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,25]]},"references-count":66,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/clr.13699"],"URL":"https:\/\/doi.org\/10.1111\/clr.13699","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,25]]},"assertion":[{"value":"2020-08-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}