{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T13:00:47Z","timestamp":1765976447816,"version":"3.40.5"},"reference-count":75,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T00:00:00Z","timestamp":1611705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To retrospectively evaluate the conditions of the peri\u2010implant tissues in treated patients with chronic periodontitis (CP) and in patients without chronic periodontitis (noCP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A chart review was used to evaluate 267 implants, 134 placed in 42 CP treated patients and 133 placed in 46 noCP patients. The primary outcome was to evaluate the condition of the peri\u2010implant tissues (health, peri\u2010mucositis, and peri\u2010implantitis). The secondary outcome was to evaluate the possible association of some variables, such as, Plaque Index (PI), Bleeding Index (BI), probing pocket depth (PD), bleeding on probing (BoP), bone level (BL), loading time, type of implant placement and loading protocol, type of prosthesis, type of bone, implant manufacturer, and implant diameter and length, with the implant health condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The analysis of patient files revealed that after 10\u201315\u00a0years of loading (mean loading time 13.4\u00a0\u00b1\u00a02.07\u00a0years), six noCP patients (13%) experienced implant loss with a total of nine implants (6.7%) lost. The remaining 124 implants were classified: 54 (43.5%) as healthy, 45 (36.3%) with peri\u2010implant mucositis, and 25 (20.2%) with peri\u2010implantitis. Twelve CP subjects (28.5%) experienced implant loss with a total of 19 implants (14.1%) lost. The remaining 115 implants were classified: 34 (29.5%) as healthy, 40 (34.7%) with peri\u2010implant mucositis and 41 (35.6%) with peri\u2010implantitis. Compared with noCP subjects, only treated CP subjects with recurrent periodontal disease (RPD) showed differences statistically significant (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>After 10\u201315\u00a0years of loading, in CP patients treated in a private practice setting, most implants (70.1%) were classified with some type of peri\u2010implant inflammation. In patients with RPD, a higher tendency for implant loss and peri\u2010implant biologic complications was found.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.13712","type":"journal-article","created":{"date-parts":[[2021,1,16]],"date-time":"2021-01-16T10:57:16Z","timestamp":1610794636000},"page":"422-436","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of peri\u2010implant tissues condition after 10\u201315 years of loading in treated chronic periodontitis patients attending a private practice setting: A retrospective study"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1449-8340","authenticated-orcid":false,"given":"Renzo","family":"Guarnieri","sequence":"first","affiliation":[{"name":"Department of Dental and Maxillofacial Sciences School of Dentistry University La Sapienza Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Di Nardo","sequence":"additional","affiliation":[{"name":"Department of Dental and Maxillofacial Sciences School of Dentistry University La Sapienza Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianni","family":"Di Giorgio","sequence":"additional","affiliation":[{"name":"Department of Dental and Maxillofacial Sciences School of Dentistry University La Sapienza Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Miccoli","sequence":"additional","affiliation":[{"name":"Department of Dental and Maxillofacial Sciences School of Dentistry University La Sapienza Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Testarelli","sequence":"additional","affiliation":[{"name":"Department of Dental and Maxillofacial Sciences School of Dentistry University La Sapienza Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,27]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"33","article-title":"Diagnosis and treatment of refractory periodontitis","volume":"2","author":"Adams D.","year":"1992","journal-title":"Current Opinion in Dentistry"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2010.01977.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12462"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0b013e3181bb8f6c"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.1"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2004.tb00213.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2013.09.013"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.29.s3.12.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12185"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02258.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02264.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2014.09.013"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02424.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034513504950"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2014.140438"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01750.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515608832"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13264"},{"key":"e_1_2_8_20_1","first-page":"937","article-title":"Could cytokine levels in the peri\u2010implant crevicular fluid be used to distinguish between healthy implants and implants with peri\u2010implantitis? A systematic review","volume":"26","author":"Duarte P. M.","year":"2015","journal-title":"Clinical Oral Implants Research"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01772.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1993.tb00706.x"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.140603"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01247.x"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2018.09.010"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.01001.x"},{"key":"e_1_2_8_27_1","first-page":"613","article-title":"Retrospective study of the long\u2010term survival of 980 implants placed in a periodontal practice","volume":"25","author":"Garc\u00eda\u2010Bellosta S.","year":"2010","journal-title":"International Journal of Oral Maxillofacial Implants"},{"key":"e_1_2_8_28_1","first-page":"1","article-title":"Use of IL\u20101 \u03b2, IL\u20106, TNF\u2010\u03b1, and MMP\u20108 biomarkers to distinguish peri\u2010implant diseases: A systematic review and metaanalysis","author":"Ghassib I.","year":"2018","journal-title":"Clinical Implant Dentistry and Related Research"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-017-2104-4"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1988.tb01017.x"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1978.49.5.225"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2002.130402.x"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01406.x"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.000.00934.x"},{"key":"e_1_2_8_35_1","first-page":"173","article-title":"How do smoking, diabetes, and periodontitis affect outcomes of implant treatment?","volume":"22","author":"Klokkevold P. R.","year":"2007","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01659.x"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2011.00415.x"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01674.x"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/ma11101802"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1999.100501.x"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01745.x"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01283.x"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02476.x"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2010.01945.x"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1563\/1548-1336(2008)34[269:PDMBAW]2.0.CO;2"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2012.01872.x"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1995.tb00123.x"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1987.tb00298.x"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2009.00244.x"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2007.00076.x"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01207.x"},{"issue":"2","key":"e_1_2_8_52_1","first-page":"442","article-title":"The use of tapered implants in the maxillae of periodontally susceptible patients: 10\u2010year outcomes","volume":"27","author":"Ormianer Z.","year":"2012","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070415.x"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0721"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12052"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2004.01120.x"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01194.x"},{"key":"e_1_2_8_58_1","first-page":"811","article-title":"Microbial community composition on modified dental implant surfaces: An in vivo study","volume":"27","author":"Rehman A.","year":"2012","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01416.x"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12227"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01886.x"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12800"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00906.x"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00908.x"},{"issue":"3","key":"e_1_2_8_65_1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1708-8208.2009.00162.x","article-title":"Risk of implant failure and marginal bone loss in subjects with a history of periodontitis: A systematic review and meta\u2010analysis","volume":"12","author":"Safi S. H.","year":"2010","journal-title":"Clinical Implant Dentistry and Related Research"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2015.10.010"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01837.x"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01347.x"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12609"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.16-0350"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12319"},{"key":"e_1_2_8_72_1","first-page":"831","article-title":"Systemic antibiotics in periodontitis","volume":"67","author":"Slots J.","year":"1996","journal-title":"Journal of Periodontology"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12684"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.18-0006"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.4149"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00708.x"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.13712","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/clr.13712","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.13712","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T14:24:52Z","timestamp":1724336692000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/clr.13712"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,27]]},"references-count":75,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1111\/clr.13712"],"URL":"https:\/\/doi.org\/10.1111\/clr.13712","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"type":"print","value":"0905-7161"},{"type":"electronic","value":"1600-0501"}],"subject":[],"published":{"date-parts":[[2021,1,27]]},"assertion":[{"value":"2020-01-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}