{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T19:22:59Z","timestamp":1791141779209,"version":"4.1.0"},"reference-count":50,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T00:00:00Z","timestamp":1665014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003142","name":"Fonds NutsOhra","doi-asserted-by":"publisher","award":["1303\u2010042"],"award-info":[{"award-number":["1303\u2010042"]}],"id":[{"id":"10.13039\/501100003142","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To prospectively assess the clinical performance and patient\u2010reported outcomes of dental implants in dentate patients with primary and secondary Sj\u00f6gren's syndrome (pSS and sSS, respectively) compared to patients without SS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Thirty\u2010seven implants were placed in 17 patients with pSS\/sSS and 26 implants in 17 non\u2010SS patients to replace missing (pre)molars. Clinical performance, marginal bone\u2010level changes, patient satisfaction, and oral health\u2010related quality of life (OHRQoL) were assessed at 1 (T1), 6 (T6), 12 (T12), and 18 (T18) months after placement of the superstructure. Marginal bone\u2010level changes were measured on standardized dental radiographs. Clinical parameters included implant and crown survival, plaque, bleeding and gingival indices, and probing depth. Patient satisfaction and OHRQoL were assessed with validated questionnaires.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Implant survival at T18 was 100% in the patients with pSS\/sSS and 96.2% in the non\u2010SS group. Mean marginal bone loss at T18 did not differ between patients with pSS\/sSS and non\u2010SS patients, 1.10\u2009\u00b1\u20091.04\u00a0and 1.04\u2009\u00b1\u20090.75\u2009mm, respectively (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.87). Clinical performance was good with no differences between the groups for all outcome measures (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05). OHRQoL in patients with pSS\/sSS had improved significantly after placement of implant supported crowns at all measuring moments compared to baseline (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). Nevertheless, patient satisfaction and OHRQoL remained significantly higher for patients without SS at all measuring moments (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Dental implants can be successfully applied in dentate patients with pSS\/sSS and have a positive effect on OHRQoL.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.13998","type":"journal-article","created":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T14:53:10Z","timestamp":1663858390000},"page":"1157-1170","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Dental implants in dentate primary and secondary Sj\u00f6gren's syndrome patients: A multicenter prospective cohort study"],"prefix":"10.1111","volume":"33","author":[{"given":"Floor","family":"Maarse","sequence":"first","affiliation":[{"name":"Department of Maxillofacial Surgery and Oral Pathology Amsterdam UMC and Academic Centre for Dentistry Amsterdam (ACTA), Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willem M. M.","family":"Fennis","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Prosthodontics and Special Dental Care University Medical Center Utrecht  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos W. R.","family":"Twisk","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Data Science, Amsterdam UMC Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anke","family":"Korfage","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Groningen, University Medical Center Groningen  Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendrik\u00a0J.","family":"Santing","sequence":"additional","affiliation":[{"name":"Private Dental Practice Bocht Oosterdiep  Veendam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurens","family":"den Hartog","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Groningen, University Medical Center Groningen  Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marvick S. M.","family":"Muradin","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Prosthodontics and Special Dental Care University Medical Center Utrecht  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melvin\u00a0S.","family":"Maningky","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Surgery and Oral Pathology Amsterdam UMC and Academic Centre for Dentistry Amsterdam (ACTA), Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerry M.","family":"Raghoebar","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Groningen, University Medical Center Groningen  Groningen The 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