{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:35:38Z","timestamp":1791891338896,"version":"4.3.4"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,2,12]],"date-time":"2023-02-12T00:00:00Z","timestamp":1676160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To examine early bone healing around implants with non\u2010modified and modified surfaces.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material &amp; Methods<\/jats:title><jats:p>Four implants with 4 different surface characteristics were installed in one side of the mandible following tooth extraction in 6 dogs. Implants in group A had a non\u2010modified, turned surface, while implants in group B had a surface modification consisting of TiO\u2010blasting and sequential acid\u2010etching in oxalic and hydrofluoric acid. The surface modification of implants in group C was confined to sequential acid\u2010etching in oxalic and hydrofluoric acid and Group D implants had a surface modification of TiO\u2010blasting and acid\u2010etching in hydrofluoric acid. The implant installation procedures were repeated in the opposite side of the mandible 4\u2009weeks later. Biopsies were obtained and prepared for histological analysis 2\u2009weeks later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>B and C implants had a higher degree of bone\u2010to\u2010implant contact (BIC%) than A and D implants at 2\u2009weeks of healing. At 6\u2009weeks of healing, the BIC% was higher at B than at A, C and D implants, and higher at C implants than at A implants. The amount of newly formed bone in contact with the implant within the defect area at 2\u2009weeks was higher at implants with modified surfaces (groups B, C and D) than at implants with a non\u2010modified surface (group A). Corresponding results at 6\u2009weeks were superior at B implants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>It is suggested that an implant surface modification with acid\u2010etching in oxalic and hydrofluoric acid promotes early formation of bone\u2010to\u2010implant contact.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14041","type":"journal-article","created":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T03:49:17Z","timestamp":1674791357000},"page":"312-319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Early bone healing to implants with different surface characteristics. 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