{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:44:14Z","timestamp":1787510654581,"version":"build-2736575974"},"reference-count":50,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:00:00Z","timestamp":1677024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To retrospectively assess clinical and radiographic outcomes of immediately loaded full\u2010arch fixed prostheses supported by axial and tilted implants up to 15\u2009years of function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Patients with one completely edentulous arch received an immediate full\u2010arch fixed prosthesis supported by two anterior axial and two posterior tilted implants. Definitive prosthesis consisting of a CAD\u2010CAM titanium framework and acrylic teeth was delivered 6\u00a0months later. Patients were regularly followed to assess clinical parameters and marginal bone level (MBL) change. Multilevel regression analysis was performed to investigate factors affecting implant failure and MBL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Six hundred ninety\u2010two implants were placed in 72 maxillae and 101 mandibles. Seven maxillary implants (5 axial and 2 tilted) in 6 patients and 12 mandibular implants (6 axial and 6 tilted) in 5 patients failed. 15\u2010year cumulative implant survival was 97.51% and 96.91% in maxilla and mandible, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.64). After 10\u2009years, the difference in MBL between axial and tilted implants was not significant in the maxilla (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.47, 65 patients), while it was in the mandible (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001, 80 patients). Significant higher bone loss was reported in the mandible at both 5\u2010 and 10\u2010year follow\u2010up (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001 and\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.004, respectively). Mixed\u2010effect multilevel linear regression evidenced a correlation between arch and bone loss at 5\u2010 and 10\u2010year follow\u2010up, while no correlation was found with age, gender, smoking, diabetes, and history of periodontal disease.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This long\u2010term study suggests that the present technique can be considered a viable treatment modality for the immediate rehabilitation of both maxilla and mandible.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.14047","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:35:00Z","timestamp":1675989300000},"page":"351-366","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Clinical outcomes of full\u2010arch immediate fixed prostheses supported by two axial and two tilted implants: A retrospective cohort study with 12\u201315\u2009years of follow\u2010up"],"prefix":"10.1111","volume":"34","author":[{"given":"Enrico Luigi","family":"Agliardi","sequence":"first","affiliation":[{"name":"Advanced Oral Surgery Unit, Department of Dentistry Vita Salute University, San Raffaele Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3052-8186","authenticated-orcid":false,"given":"Alessandro","family":"Pozzi","sequence":"additional","affiliation":[{"name":"Dental College of Georgia  Augusta USA"},{"name":"Private Practice in Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Romeo","sequence":"additional","affiliation":[{"name":"Advanced Oral Surgery Unit, Department of Dentistry Vita Salute University, San Raffaele Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7144-0984","authenticated-orcid":false,"given":"Massimo","family":"Del\u00a0Fabbro","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences Universit\u00e0 degli Studi di Milano  Milan Italy"},{"name":"UOC Maxillofacial Surgery and Dentistry Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,22]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.16suppl.g1"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01852.x"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2014.07.017"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12020"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2001.tb00127.x"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10266-017-0304-7"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10266-021-00605-4"},{"issue":"2","key":"e_1_2_12_9_1","first-page":"209","article-title":"An overview on bone reconstruction of atrophic maxilla: Success parameters and critical issues","volume":"30","author":"Baj A.","year":"2016","journal-title":"Journal of Biological Regulators & Homeostatic Agents"},{"key":"e_1_2_12_10_1","first-page":"1","article-title":"Osseointegrated implants in the treatment of the edentulous jaw. 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