{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T04:17:13Z","timestamp":1780633033910,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011970","name":"International Team for Implantology","doi-asserted-by":"publisher","award":["1447_2019"],"award-info":[{"award-number":["1447_2019"]}],"id":[{"id":"10.13039\/501100011970","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report the 1\u2010year implant survival\/success and peri\u2010implant outcomes of mandibular overdentures retained by four titanium\u2010zirconium mini implants (Straumann\u00ae Mini Implant System), and to assess how surgery and loading protocols influence these outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A 2\u2009\u00d7\u20092 factorial randomized clinical trial (RCT) tested the combined effects of two loading protocols (immediate or delayed) and two surgical approaches (flapless or flapped) on the success\/survival of the mini implants, and peri\u2010implant parameters (plaque, bleeding, sulcus depth, gingival position, and marginal bone loss). Outcomes were assessed up to 1\u2010year after loading, and generalized estimating equations (GEEs) were used to analyze longitudinal and within\u2010patient clustered data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred and ninety\u2010six implants were placed in 74 patients. The implant survival\/success rates after 1\u2009year were 100%, and no major biological complications were observed. After 1\u2010year, descriptive data suggest no noticeable changes in plaque scores, whilst a reduction in bleeding scores at the 6\u2010month and 1\u2010year follow\u2010ups compared to baseline. Good longitudinal stability was observed for the probing depth and gingival margin height measures. Overall mean marginal bone loss was 0.68 (\u00b10.68) mm after 3\u2009months and 0.89 (\u00b10.75) mm after 1\u2010year. The flapless protocol showed better results on soft tissue stability and health but a slightly higher risk for marginal bone loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of this RCT suggest that mandibular overdentures retained by this novel mini implant system represent a safe and predictable treatment option as confirmed by implant survival\/success and peri\u2010implant outcomes, even when flapless surgery and immediate loading protocols are adopted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14102","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T09:24:13Z","timestamp":1685525053000},"page":"769-782","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Implant survival\/success and peri\u2010implant outcomes of titanium\u2010zirconium mini implants for mandibular overdentures: Results from a 1\u2010year randomized clinical trial"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1912-4217","authenticated-orcid":false,"given":"Thalita Fernandes Fleury","family":"Curado","sequence":"first","affiliation":[{"name":"School of Dentistry Federal University of Goias  Goiania Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2152-9654","authenticated-orcid":false,"given":"J\u00e9sio Rodrigues","family":"Silva","sequence":"additional","affiliation":[{"name":"School of Dentistry Federal University of Goias  Goiania Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lays Noleto","family":"Nascimento","sequence":"additional","affiliation":[{"name":"School of Dentistry Federal University of Goias  Goiania Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luiz Rodrigues","family":"Leles","sequence":"additional","affiliation":[{"name":"Paulista University  Goiania Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8478-1673","authenticated-orcid":false,"given":"Gerald","family":"McKenna","sequence":"additional","affiliation":[{"name":"Centre for Public Health Queen's University Belfast  Belfast UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9700-5534","authenticated-orcid":false,"given":"Martin","family":"Schimmel","sequence":"additional","affiliation":[{"name":"Department of Reconstructive Dentistry, Division of Gerodontology School of Dental Medicine of the University of Bern  Bern Switzerland"},{"name":"Division of Gerodontology and Removable Prosthodontics University Clinics of Dental Medicine, University of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6812-4849","authenticated-orcid":false,"given":"Cl\u00e1udio Rodrigues","family":"Leles","sequence":"additional","affiliation":[{"name":"School of Dentistry Federal University of Goias  Goiania Brazil"},{"name":"Department of Reconstructive Dentistry, Division of Gerodontology School of Dental Medicine of the University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708\u20108208.2010.00324.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12461"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2021.11.010"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708\u20108208.2012.00456.x"},{"issue":"5","key":"e_1_2_11_6_1","first-page":"392","article-title":"Immediate loading of two unsplinted mandibular implants in edentulous patients with an implant\u2010retained overdenture: An observational study over two years","volume":"122","author":"B\u00fcttel A. 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