{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T16:46:51Z","timestamp":1793378811968,"version":"4.5.0"},"reference-count":32,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,7,23]],"date-time":"2023-07-23T00:00:00Z","timestamp":1690070400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To compare subepithelial connective tissue grafts (SCTG) versus guided bone regeneration (GBR) for the treatment of small peri\u2010implant dehiscence defects in terms of profilometric (primary outcome), clinical, and patient\u2010reported outcome measures (PROMs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixteen patients who presented with small buccal bone dehiscences (\u22643\u2009mm) following single implant placement were recruited. Following implant placement, buccal bone defect sites were randomly treated either with a SCTG or GBR. Six patients who lacked bone dehiscences after implant placement were assigned to a negative control. Transmucosal healing was applied in all patients. Patients were examined prior (T1) and after (T2) implant placement, at suture removal (T3), at implant impression (T5), at crown delivery (T6), and 12 (T7) months after crown delivery. Measurements included profilometric outcomes, marginal bone levels, buccal bone and soft tissue thickness, PROMs, and clinical parameters. All data were analyzed descriptively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median changes in buccal contour as assessed by profilometric measures between T1 and T5 showed a decrease of 1.84\u2009mm for the SCTG group and 1.06\u2009mm for the GBR group. Between T2 and T7, the median change in the buccal contour amounted to 0.45\u2009mm for SCTG and \u22120.94\u2009mm (=loss) for GBR. Patients' pain perception tended to be higher in SCTG than in GBR. All peri\u2010implant soft tissue parameters showed healthy oral tissues and no clinically relevant differences between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Within the limitations of this pilot study, treating small peri\u2010implant dehiscence defects with a SCTG might be a viable alternative to GBR. The use of a SCTG tended to result in more stable profilometric outcomes and comparable clinical outcomes to GBR. However, patient\u2010reported outcome measures tended to favor GBR.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14140","type":"journal-article","created":{"date-parts":[[2023,7,23]],"date-time":"2023-07-23T12:19:40Z","timestamp":1690114780000},"page":"1094-1105","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Randomized controlled pilot study comparing small buccal defects around dental implants treated with a subepithelial connective tissue graft or with guided bone regeneration"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9941-3491","authenticated-orcid":false,"given":"A. N.","family":"Zuercher","sequence":"first","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5832-7327","authenticated-orcid":false,"given":"F. J.","family":"Strauss","sequence":"additional","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4219-3395","authenticated-orcid":false,"given":"P. N.","family":"Paqu\u00e9","sequence":"additional","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8562-1580","authenticated-orcid":false,"given":"S. P.","family":"Bienz","sequence":"additional","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2055-1320","authenticated-orcid":false,"given":"R. E.","family":"Jung","sequence":"additional","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1764-7447","authenticated-orcid":false,"given":"D. S.","family":"Thoma","sequence":"additional","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,23]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070303.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13583"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13927"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1991.020206.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13906"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13691"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13587"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13006"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01269.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.050296"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13685"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2001.012001009.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12806"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13084"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12155"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12845"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.14029"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.22\u20100499"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13293"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2010.01987.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2011.02214.x"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13767"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010022\u201004582\u2010y"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13050"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13798"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.22\u20100226"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13114"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12465"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12588"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12223"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13920"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12948"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.14140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T23:50:14Z","timestamp":1697068214000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/clr.14140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,23]]},"references-count":32,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1111\/clr.14140"],"URL":"https:\/\/doi.org\/10.1111\/clr.14140","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,23]]},"assertion":[{"value":"2023-01-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}