{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:02:23Z","timestamp":1789624943368,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T00:00:00Z","timestamp":1698105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008364","name":"Tandl\u00e6geforeningen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008364","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Dental implant treatment is considered contraindicated in patients with cancer on high\u2010dose antiresorptive medication (HDAR). The aim of this prospective, feasibility study was to evaluate implant treatment in patients with cancer on HDAR, in terms of implant survival, implant success, and oral health\u2010related quality of life (OHLQoL) after 2\u2009years of loading.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Implants were inserted in three groups of HDAR patients: (1) Previous tooth extraction, no medication\u2010related osteonecrosis of the jaw (MRONJ), (2) Previous MRONJ, now healed, (3) Existing MRONJ, planned surgical resection. Implants were placed without adjunctive bone or soft tissue augmentation. [Correction added on 01 February 2024, after first online publication: The spelling has been corrected from \u201cargumentation\u201d to \u201caugmentation\u201d in this latest version of the article.] Abutment operation was performed after \u226512\u2009weeks. Prosthetic treatment was initiated \u226514\u2009weeks. Survival and success rate were determined, and OHLQoL was analyzed with OHIP\u201049 and QLQ\u2010H&amp;N35 questionnaires. Patients were seen for 6\u2009months, 1\u2010 and 2\u2009years follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010two patients, 39 implants, completed the implant\u2010based prosthetic treatment. Implant\u2010supported crowns and overdentures were fabricated. Thirteen patients (59%) with 23 implants (59%) completed 2\u2009years follow\u2010up. Overall implant survival and success rate after 2\u2009years of loading were 100% and 97.4%, respectively. OHLQoL for the patients increased in all groups after the treatment, a substantial increase was seen in group 3. Two patients developed MRONJ, but not related to the implant treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Dental implant treatment, with high survival and success rate and increased post\u2010treatment OHLQoL, is feasible in HDAR patients after 2\u2009years of loading. Caution with general recommendations should be exercised.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14197","type":"journal-article","created":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T11:00:52Z","timestamp":1698145252000},"page":"63-76","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Dental implant treatment in patients with cancer on high\u2010dose antiresorptive medication: A prospective feasibility study with 2\u2009years follow\u2010up"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2587-8672","authenticated-orcid":false,"given":"C. 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