{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T17:35:56Z","timestamp":1791048956808,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T00:00:00Z","timestamp":1707350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To simulate the replacement of a premolar with an implant\u2010supported cantilever fixed dental prosthesis (ICFDP) and how the fracture load is affected by implant type, positioning within the zirconia blank, and aging protocol.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Seventy\u2010two ICFDPs were designed either within the enamel\u2010 or dentin layer of a 4Y\u2010PSZ blank for bone\u2010level and tissue\u2010level titanium\u2010zirconium implants. Fracture load was obtained on the cantilever at baseline (no aging) or after aging in a chewing simulator with the load applied within the implant axis (axial aging) or on the cantilever (12 groups with <jats:italic>n<\/jats:italic>\u2009=\u20096). A three\u2010way ANOVA was applied (<jats:italic>\u03b1<\/jats:italic>\u2009=\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A three\u2010way ANOVA revealed a significant effect on fracture load values of implant type (<jats:italic>p<\/jats:italic>\u2009=\u2009.006) and aging (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) but not for the position within the zirconia blank (<jats:italic>p<\/jats:italic>\u2009=\u2009.847). Fracture load values significantly increased from baseline bone level (608\u2009\u00b1\u2009118\u2009N) and tissue level (880\u2009\u00b1\u2009293\u2009N) when the implants were aged axially, with higher values for tissue level (1065\u2009\u00b1\u2009182\u2009N) than bone level (797\u2009\u00b1\u2009113\u2009N) (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). However, when the force was applied to the cantilever, fracture load values decreased significantly for tissue\u2010level (493\u2009\u00b1\u200970\u2009N), while values for bone\u2010level implants remained stable (690\u2009\u00b1\u2009135\u2009N).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>For ICFDPs, the use of bone\u2010level implants is reasonable as catastrophic failures are likely to be restricted to the restoration, whereas with tissue\u2010level implants, the transmucosal portion of the implant is susceptible to deformation, making repair more difficult.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14240","type":"journal-article","created":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T12:04:31Z","timestamp":1707393871000},"page":"419-426","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effect of implant type on the stability of cantilever fixed dental prostheses: An in\u00a0vitro study"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1218-4519","authenticated-orcid":false,"given":"Nadja","family":"Rohr","sequence":"first","affiliation":[{"name":"Biomaterials and Technology, Department of Research University Center for Dental Medicine Basel UZB, University of Basel  Basel Switzerland"},{"name":"Department of Reconstructive Dentistry University Center for Dental Medicine Basel UZB, University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Karakas\u2010Stupar","sequence":"additional","affiliation":[{"name":"Department of Reconstructive Dentistry University Center for Dental Medicine Basel UZB, University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Karlin","sequence":"additional","affiliation":[{"name":"Biomaterials and Technology, Department of Research University Center for Dental Medicine Basel UZB, University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8228-6545","authenticated-orcid":false,"given":"Nicola U.","family":"Zitzmann","sequence":"additional","affiliation":[{"name":"Department of Reconstructive Dentistry University Center for Dental Medicine Basel UZB, University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4640-7274","authenticated-orcid":false,"given":"Lucia K.","family":"Zaugg","sequence":"additional","affiliation":[{"name":"Department of Reconstructive Dentistry University Center for Dental Medicine Basel UZB, University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02391.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/jispcd.JISPCD_138_20"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.11607\/ijp.7576"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/10255842.2017.1287905"},{"key":"e_1_2_11_6_1","doi-asserted-by":"crossref","first-page":"s192","DOI":"10.11607\/jomi.16suppl.g5.3","article-title":"Maxillary implant\u2010supported fixed prosthesis: A survey of reviews and key variables for treatment planning","volume":"31","author":"Gallucci G. 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