{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:43:45Z","timestamp":1792590225344,"version":"4.5.0"},"reference-count":51,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T00:00:00Z","timestamp":1708300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The effect of the implant position within the prosthesis on bone remodeling is scarcely documented so far. Thus, the aim of the present study was to investigate whether central implants may suffer higher peri\u2010implant marginal bone levels (MBL) compared to laterals in case of fixed splinted bridges supported by \u2265 three implants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Partially edentulous subjects rehabilitated with at least one fixed bridge supported by \u2265 three dental implants were enrolled. MBL was assessed radiographically by means of intraoral radiographs acquired with phosphor plates and imported in a dedicated software. MBL was calculated as the distance between the implant platform level and the most coronal visible bone\u2010to\u2010implant contact. A three\u2010level linear mixed effects model was used for investigating the fixed effect of patient\u2010, prosthesis\u2010, and implant\u2010level variables on the MBL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 90 patients rehabilitated with 130 splinted fixed bridges supported by 412 implants were included. The median follow\u2010up was 136\u2009months. The mean peri\u2010implant MBL resulted statistically significantly higher at central implants if compared to lateral implants (<jats:italic>p\u2009&lt;\u2009.01<\/jats:italic>). The estimated MBL averages for central and external implants were 1.68 and 1.18\u2009mm, respectively. The prosthesis\u2010level variables suggested that a cement\u2010retained bridge was prone to a significant 0.82\u2009mm higher MBL than a screw\u2010retained one. Implant surface showed an association with MBL changes, although less pronounced than implant retention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In case of \u22653 adjacent implants supporting splinted bridges, central implants were more predisposed to MBL compared to laterals. At the prosthesis level, implants supporting cement\u2010retained bridges were statistically more susceptible to MBL compared to screw\u2010retained ones. Surface characteristics can also influence MBL stability at the implant level.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14250","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T12:05:11Z","timestamp":1708344311000},"page":"547-559","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Radiographic evaluation of marginal bone levels around implants supporting splinted fixed bridges: A retrospective study on 412 implants"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8270-763X","authenticated-orcid":false,"given":"Mattia","family":"Manfredini","sequence":"first","affiliation":[{"name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Implant Center for Edentulism and Jawbone Atrophies Maxillofacial Surgery and Odontostomatology Unit  Milan Italy"},{"name":"Department of Biomedical Surgical and Dental Sciences, University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3739-1490","authenticated-orcid":false,"given":"Pier Paolo","family":"Poli","sequence":"additional","affiliation":[{"name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Implant Center for Edentulism and Jawbone Atrophies Maxillofacial Surgery and Odontostomatology Unit  Milan Italy"},{"name":"Department of Biomedical Surgical and Dental Sciences, University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2649-2192","authenticated-orcid":false,"given":"Mario","family":"Beretta","sequence":"additional","affiliation":[{"name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Implant Center for Edentulism and Jawbone Atrophies Maxillofacial Surgery and Odontostomatology Unit  Milan Italy"},{"name":"Department of Biomedical Surgical and Dental Sciences, University of Milan  Milan 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