{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T18:17:50Z","timestamp":1789237070365,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T00:00:00Z","timestamp":1717718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the accuracy of artificial intelligence (AI)\u2010based segmentation of the mandibular canal, compared to the conventional manual tracing, implementing implant planning software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Localization of the mandibular canals was performed for 104 randomly selected patients. A localization was performed by three experienced clinicians in order to serve as control. Five tracings were performed: One from a clinician with a moderate experience with a manual tracing (I<jats:sub>1<\/jats:sub>), followed by the implementation of an automatic refinement (I<jats:sub>2<\/jats:sub>), one manual from a dental student (S<jats:sub>1<\/jats:sub>), and one from the experienced clinician, followed by an automatic refinement (E). Subsequently, two fully automatic AI\u2010driven segmentations were performed (A<jats:sub>1<\/jats:sub>,A<jats:sub>2<\/jats:sub>). The accuracy between each method was measured using root mean square error calculation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The discrepancy among the models of the mandibular canals, between the experienced clinicians and each investigated method ranged from 0.21 to 7.65\u2009mm with a mean of 3.5\u2009mm RMS error. The analysis of each separate mandibular canal's section revealed that mean RMS error was higher in the posterior and anterior loop compared to the middle section. Regarding time efficiency, tracing by experienced users required more time compared to AI\u2010driven segmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The experience of the clinician had a significant influence on the accuracy of mandibular canal's localization. An AI\u2010driven segmentation of the mandibular canal constitutes a time\u2010efficient and reliable procedure for pre\u2010operative implant planning. Nevertheless, AI\u2010based segmentation results should always be verified, as a subsequent manual refinement of the initial segmentation may be required to avoid clinical significant errors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14307","type":"journal-article","created":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T08:14:41Z","timestamp":1717748081000},"page":"1163-1171","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Accuracy of artificial intelligence\u2010based segmentation of the mandibular canal in CBCT"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1349-2548","authenticated-orcid":false,"given":"Panagiotis","family":"Ntovas","sequence":"first","affiliation":[{"name":"Department of Prosthodontics, School of Dental Medicine Tufts University School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Marchand","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, School of Dental Medicine Tufts University School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Finkelman","sequence":"additional","affiliation":[{"name":"Department of Public Health and Community Service Tufts University School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Revilla\u2010Le\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, School of Dental Medicine Tufts University School of Dental Medicine  Boston Massachusetts USA"},{"name":"Department of Restorative Dentistry, School of Dentistry University of Washington  Seattle Washington USA"},{"name":"Faculty and Director of Research and Digital Dentistry, Kois Center  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wael","family":"Att","sequence":"additional","affiliation":[{"name":"Medical Center University of Freiburg, Center for Dental Medicine, Department of Prosthetic Dentistry  Freiburg Germany"},{"name":"Private Practice, The Face Dental Group  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11548\u2010016\u20101484\u20102"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010016\u20102014\u2010x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20150298"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20130291"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jebdp.2017.05.002"},{"issue":"4","key":"e_1_2_10_7_1","first-page":"68","article-title":"Systematic interpretation of CBCT scans: Why do it?","volume":"62","author":"Ganguly R.","year":"2014","journal-title":"Journal of the Massachusetts Dental Society"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20220279"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010006\u20100089\u20105"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17124424"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13010110"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2019.12.011"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19010560"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201062321\u20103"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010022\u201017341\u20106"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20103\u2010642\u201004271\u20103_10"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jds.2020.06.019"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201062586\u20108"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2020.12.020"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2021.103891"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40902\u2010015\u20100030\u20104"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14539"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.03.023"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903\u2010021\u201001983\u20105"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010021\u201004082\u20105"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010022\u201004708\u20102"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010023\u201037798\u20103"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2011.03.038"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/8897275"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2021.05.008"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.5037\/jomr.2014.5402"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.2014suppl.g1.2"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2017.12.026"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/s22249877"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2021.103786"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010019\u201045487\u20103"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2019.06.026"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2023.104727"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.14307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T12:55:47Z","timestamp":1727700947000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/clr.14307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,7]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1111\/clr.14307"],"URL":"https:\/\/doi.org\/10.1111\/clr.14307","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,7]]},"assertion":[{"value":"2024-03-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}