{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T22:14:47Z","timestamp":1780956887741,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the early impact of plaque accumulation in a buccal dehiscence defect on peri\u2010implant marginal bone resorption.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In six male Mongrel dogs, four dental implants were placed in the posterior maxilla on both sides (two implants per side). Based on the group allocation, each implant was randomly assigned to one of the following four groups to decide whether buccal dehiscence defect was prepared and whether silk ligation was applied at 8\u2009weeks post\u2010implant placement for peri\u2010implantitis induction: UC (no defect without ligation); UD (defect without ligation); LC (no defect with ligation); and LD (defect with ligation) groups. Eight weeks after disease induction, the outcomes from radiographic and histologic analyses were statistically analyzed (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Based on radiographs, the exposed area of implant threads was smallest in group UC (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.0083). Based on histology, both the distances from the implant platform to the first bone\u2010to\u2010implant contact point and to the bone crest were significantly longer in the LD group (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.0083). In the UD group, some spontaneous bone fill occurred from the base of the defect at 8\u2009weeks after implant placement. The apical extension of inflammatory cell infiltrate was significantly more prominent in the LD and LC groups compared to the UC group (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.0083).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Plaque accumulated on the exposed implant surface had a negative impact on maintaining the peri\u2010implant marginal bone level, especially when there was a dehiscence defect around the implant.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14324","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T13:55:38Z","timestamp":1719842138000},"page":"1373-1381","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Does an untreated peri\u2010implant dehiscence defect affect the progression of peri\u2010implantitis?: A preclinical in\u00a0vivo experimental study"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1835-5646","authenticated-orcid":false,"given":"Young Woo","family":"Song","sequence":"first","affiliation":[{"name":"Department of Periodontology, Dental Hospital Veterans Health Service Medical Center  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6408-1618","authenticated-orcid":false,"given":"Jin\u2010Young","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Periodontology Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji\u2010Yeong","family":"Na","sequence":"additional","affiliation":[{"name":"Department of Periodontology Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry  Seoul South 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