{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T17:15:21Z","timestamp":1787591721324,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:00:00Z","timestamp":1720051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100016070","name":"ITI Foundation","doi-asserted-by":"publisher","award":["1391_2019"],"award-info":[{"award-number":["1391_2019"]}],"id":[{"id":"10.13039\/501100016070","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare early implant placement (EP) to alveolar ridge preservation and delayed implant placement (ARP\/DP) in terms of contour changes, along with clinician\u2010 and patient\u2010reported outcome measures (PROMs) until the delivery of the implant\u2010supported restoration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Patients with a failing single tooth in the maxilla or mandible were recruited in two centres. After tooth extraction, patients were randomly assigned (1:1) to either EP or ARP\/DP. At abutment connection and crown delivery, the buccal contour changes at 3\u2009mm below the mucosal margin (primary outcome) along with clinician\u2010 (ease of treatment) and patient\u2010reported outcomes were assessed using numeric rating scales and OHIP\u201014.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 46 patients were analysed. The mean buccal contour at abutment connection decreased by \u22121.2\u2009\u00b1\u20090.6\u2009mm in group EP and \u22121.6\u2009\u00b1\u20090.8\u2009mm in group ARP\/DP (estimated mean difference; 0.45 [95%CI, \u22120.02; 0.94]; <jats:italic>p<\/jats:italic>\u2009=\u2009.061) with no significant differences between the groups. ARP\/DP was consistently easier than EP across all stages of the surgery (estimated mean difference; 2.0 [95%CI, 1.3; 2.7] <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001): during flap elevation (EP: 4.8 vs. ARP\/DP: 1.6), implant placement (EP: 5.7 vs. ARP\/DP: 2.2) and wound closure (EP: 3.4 vs. ARP\/DP: 1.6). Both interventions improved quality of life but patients who underwent ARP\/DP were significantly more satisfied at the time of crown delivery (ARP\/DP: 9.6 vs. EP: 9.1, <jats:italic>p<\/jats:italic>\u2009=\u2009.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>EP and ARP\/DP show no significant differences in buccal contour changes, aesthetics and patient\u2010reported outcomes. However, ARP\/DP is an easier procedure at all stages of the surgery compared to EP and could therefore be the preferred therapy for less experienced clinicians.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14325","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T10:40:15Z","timestamp":1720089615000},"page":"1382-1393","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Early implant placement versus ridge preservation and delayed implant placement: Analysis of profilometric, clinician\u2010 and patient\u2010reported outcomes from a two\u2010centre <scp>RCT<\/scp>"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1764-7447","authenticated-orcid":false,"given":"Daniel","family":"Thoma","sequence":"first","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center for Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Gil","sequence":"additional","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center for Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"de Bruyckere","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Oral Implantology, Oral Health Sciences Ghent University  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2055-1320","authenticated-orcid":false,"given":"Ronald E.","family":"Jung","sequence":"additional","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center for Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1066-7541","authenticated-orcid":false,"given":"Shunsuke","family":"Fukuba","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Graduate School of Medical and Dental Science Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axelle","family":"Ickroth","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Oral Implantology, Oral Health Sciences Ghent University  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5832-7327","authenticated-orcid":false,"given":"Franz J.","family":"Strauss","sequence":"additional","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center for Dental Medicine University of Zurich  Zurich Switzerland"},{"name":"Faculty of Dentistry Universidad Finis Terrae  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5042-2875","authenticated-orcid":false,"given":"Jan","family":"Cosyn","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Oral Implantology, Oral Health Sciences Ghent University  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,4]]},"reference":[{"issue":"2","key":"e_1_2_11_2_1","first-page":"123","article-title":"The influence of Bio\u2010Oss Collagen on healing of an extraction socket: An experimental study in the dog","volume":"28","author":"Araujo M.","year":"2008","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034520905660"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12185"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13911"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12163"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13390"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12634"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2002.73.1.94"},{"key":"e_1_2_11_10_1","first-page":"26","article-title":"Consensus statements and recommended clinical procedures regarding the placement of implants in extraction sockets","volume":"19","author":"Hammerle C. 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