{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:11:05Z","timestamp":1791389465887,"version":"4.3.3"},"reference-count":64,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T00:00:00Z","timestamp":1721001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the influence of patient and implant\u2010related factors on the changes of marginal bone levels (MBL) at implants with a follow\u2010up \u22655\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>At baseline (within 6\u2009months from prosthetic insertion) and long\u2010term (\u22655\u2009years after implant placement) visits, interproximal (mesial and distal) MBL were radiographically evaluated. To analyze factors predicting MBL change, the site (either mesial or distal) showing the highest MBL change (hChMBL site) was identified for each implant. Multilevel regression models were built to explain MBL change as well as the probability for a bone loss \u22652\u2009mm at long\u2010term.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>942 implants in 312 patients with a mean follow\u2010up of 8.02\u2009\u00b1\u20092.5\u2009years were analyzed. MBL change was significantly predicted by baseline MBL, oral bisphosphonate (BP) intake, history of periodontitis, diabetes, and super\u2010hydrophilic implant surface. Higher risk for a bone loss \u22652\u2009mm was observed in patients with history of periodontitis (OR\u2009=\u20099.52, 95% CI 0.72\u20133.79) and taking BP (OR\u2009=\u20096.84, 95% CI 0.21\u20133.63). Mandibular implants had higher odds for bone loss \u22652\u2009mm compared to maxillary implants (OR\u2009=\u20093, 95% CI 0.39\u20131.87).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The findings of the present study contribute to the identification of specific clinical scenarios at higher risk for implant\u2010supporting bone loss that need to be strictly monitored during maintenance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.14327","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T06:23:53Z","timestamp":1721024633000},"page":"1406-1417","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Factors affecting radiographic marginal bone resorption at dental implants in function for at least 5\u2009years: A multicenter retrospective study"],"prefix":"10.1111","volume":"35","author":[{"given":"Leonardo","family":"Trombelli","sequence":"first","affiliation":[{"name":"Research Centre for the Study of Periodontal and Peri\u2010Implant Diseases University of Ferrara  Ferrara Italy"},{"name":"Operative Unit of Dentistry AUSL of Ferrara  Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4621-7809","authenticated-orcid":false,"given":"Roberto","family":"Farina","sequence":"additional","affiliation":[{"name":"Research Centre for the Study of Periodontal and Peri\u2010Implant Diseases University of Ferrara  Ferrara Italy"},{"name":"Operative Unit of Dentistry AUSL of Ferrara  Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3610-6574","authenticated-orcid":false,"given":"Cristiano","family":"Tomasi","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Institute of Odontology, Sahlgrenska Academy University of Gothenburg  G\u00f6teborg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4574-3671","authenticated-orcid":false,"given":"Fabio","family":"Vignoletti","sequence":"additional","affiliation":[{"name":"Section of Periodontology, Faculty of Odontology University Complutense of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guerino","family":"Paolantoni","sequence":"additional","affiliation":[{"name":"Private Practice in Napoli  Napoli Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Giordano","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Dentistry \"Scuola Medica Salernitana\" University of Salerno  Baronissi Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Ortensi","sequence":"additional","affiliation":[{"name":"Private Practice in Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2332-7332","authenticated-orcid":false,"given":"Anna","family":"Simonelli","sequence":"additional","affiliation":[{"name":"Research Centre for the Study of Periodontal and Peri\u2010Implant Diseases University of Ferrara  Ferrara Italy"},{"name":"Operative Unit of Dentistry AUSL of Ferrara  Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,15]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022\u20103913(88)90355\u20101"},{"key":"e_1_2_10_3_1","first-page":"15","article-title":"On long\u2010term maintenance of the osseointegrated response","volume":"7","author":"Albrektsson T.","year":"1993","journal-title":"Australian Prosthodontic 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