{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:18:02Z","timestamp":1791415082572,"version":"4.3.3"},"reference-count":64,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Assess whether horizontal ridge augmentation with guided bone regeneration (GBR) using deproteinized bovine bone mineral (DBBM), autologous bone, and a resorbable collagen membrane supports successful implant placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This open, prospective, single\u2010cohort, multicenter clinical study included patients with ridge defects that required GBR prior to implant insertion. The primary endpoint was radiologically assessed bone gain after 8 months post\u2010GBR, measured at the center of planned implant sites. Secondary endpoints included implant survival and success, marginal bone levels (MBLs), MBL changes, and soft tissue health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 45 patients evaluated 8 months post\u2010GBR, nine experienced dehiscence in the first 3\u2009weeks of the healing period. GBR led to radiologically determined mean bone width gain of 4.0\u2009\u00b1\u20091.5\u2009mm and 4.8\u2009\u00b1\u20091.7\u2009mm, measured 1 and 3\u2009mm from the top of the crest, respectively, allowing successful implant placement in 44 patients (97.8%). The cumulative implant survival and success rates were 98.9% and 95.5%, respectively. MBLs were stable: \u22121.18\u2009\u00b1\u20090.64\u2009mm at definitive prosthesis placement (DPP) and \u2212 1.07\u2009\u00b1\u20090.74\u2009mm at 1 year. Soft tissue health and esthetics (plaque and bleeding indices, papilla, keratinized mucosa, and pink esthetic score) improved from DPP to 1 year. Patients were highly satisfied with implant function and esthetics, and their oral health\u2010related quality of life improved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>GBR using DBBM and a collagen membrane offered a safe and effective treatment option for horizontal ridge augmentation sufficient to support implant\u2010based tooth rehabilitation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial Registration<\/jats:title><jats:p>Registered at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link> NCT03028922 (registrations sites, as above listed affiliations, first posted January 23, 2017)<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14363","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T09:20:37Z","timestamp":1727774437000},"page":"100-116","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Horizontal Guided Bone Regeneration of the Posterior Mandible to Allow Implant Placement: 1\u2010Year Prospective Study Results"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4209-3992","authenticated-orcid":false,"given":"Jonas","family":"Lorenz","sequence":"first","affiliation":[{"name":"FORM\u2014Frankfurt Orofacial Regenerative Medicine, Clinic for Oral, Cranio\u2010Maxillofacial and Facial Plastic Surgery Medical Center of the Goethe University Frankfurt  Frankfurt am Main 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