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Dental implant (DI) placement in high\u2010dose AR (HDAR) patients is widely discouraged, and thorough counseling is recommended for low\u2010dose AR (LDAR) patients. However, data on the role of AR type, dose, and duration remain limited. This review evaluates MRONJ associated with DIs, focusing on AR type and accumulated dose, and identifies local and systemic risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This review follows the PCC framework for PRISMA\u2010ScR, comparing patients on AR who developed DI\u2010related MRONJ to those who did not, based on the available clinical evidence. A systematic search was conducted on April 13, 2024, in PubMed, Embase, and Cochrane Library. Two reviewers independently screened and extracted data; a third reviewer resolved disagreements. Data extraction included demographics, primary disease, AR type, dose, treatment duration, DI location, and MRONJ details.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 2201 articles, 28 studies were included involving 76 patients with 215 DI (154 in LDAR, 61 in HDAR). The development of MRONJ was reported in 15 studies involving LDAR and four studies on HDAR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Evidence was insufficient to confirm an association between accumulated AR dose and MRONJ associated with DIs. No specific risk factors were identified, emphasizing the need for standardized reporting on AR type, dosage, treatment duration, and intervals to facilitate comprehensive risk assessment. Until evidence\u2010based guidelines emerge, DI therapy in HDAR or long\u2010term LDAR patients should be limited to specialized centers.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14453","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T10:34:52Z","timestamp":1750242892000},"page":"1173-1201","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Medication\u2010Related Osteonecrosis of the Jaws in Patients on Antiresorptive Medication With Dental Implants. 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