{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T20:11:20Z","timestamp":1788207080283,"version":"build-2803163510"},"reference-count":48,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007619","name":"Osteology Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the medium\u2010term efficacy of using a xenogeneic collagen matrix to augment the width of the peri\u2010implant keratinized mucosa (PIKM) as an adjunct to the surgical treatment of peri\u2010implantitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>In this 36\u2010month parallel\u2010arm randomized controlled clinical trial, patients with peri\u2010implantitis were randomly assigned to a combined protocol of resective peri\u2010implantitis surgery and a PIKM augmentation procedure, either with an autologous free gingival graft (FGG) or a collagen matrix (CM). Primary outcomes were the increase in the width of PIKM and probing pocket depth (PPD) reduction at 36\u2009months. As secondary outcomes, radiographic and patient\u2010reported outcomes were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010one patients (20 in the CM group and 21 in the FGG group) completed the three\u2010year follow\u2010up. PIKM increased in both groups, but the increase was significantly higher in the APF (apically positioned flap)\u2009+\u2009FGG group compared to the APF\u2009+\u2009CM group [2.0 (95% CI: 1.3, 2.7) mm in the FGG group compared to 1.0 (95% CI: 0.5, 1.5) mm in the CM group; <jats:italic>p<\/jats:italic>\u2009=\u20090.048]. PPDs were reduced by 1.5\u2009mm (95% CI: 1.1, 1.9) and 1.4\u2009mm (95% CI: 0.6, 2.2), respectively. Disease resolution (maximum one site with bleeding on probing, no suppuration, no further bone loss &gt;\u20090.5\u2009mm, and PD \u2264\u20095\u2009mm) was 47.6% in the FGG group and 35.0% in the CM group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Tested surgical modalities resulted in similar improvements in the clinical parameters. Both FGG and CM increased the PIKM, but PIKM was greater at the 36\u2010month examination in the FGG group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.14465","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T23:05:18Z","timestamp":1750460718000},"page":"1159-1171","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Surgical Treatment of Peri\u2010Implantitis Combined With Keratinized Mucosa Augmentation: Results of a Dual\u2010Center 3\u2010Year <scp>RCT<\/scp>"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2301-5429","authenticated-orcid":false,"given":"Myroslav","family":"Solonko","sequence":"first","affiliation":[{"name":"Section of Graduate Periodontology Faculty of Odontology, University Complutense  Madrid 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