{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T10:53:04Z","timestamp":1782471184256,"version":"3.54.5"},"reference-count":57,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100030982","name":"Straumann Group","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100030982","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To compare the clinical performance of two sandblasted, large\u2010grit, acid\u2010etched implant surfaces regarding changes in radiographic marginal bone level (MBL) 12\u2009months after loading.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      In this randomized, split\u2010mouth, dual\u2010center clinical trial, each patient received one test (modified hydrophilic surface) implant and one control (conventional surface) implant. The primary endpoint was the change in MBL measured 12\u2009months after loading. Secondary outcomes included the assessment of soft tissue wound healing index (WHI), adverse events, implant stability quotient (ISQ), peri\u2010implant soft tissue parameters (probing pocket depth, bleeding on probing, keratinized mucosa width), and oral health\u2013related quality of life (OHRQoL) measured with the Oral Health Impact Profile\u201014 (OHIP\u201014). Generalized linear models, paired Student's\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests, and Wilcoxon tests were employed for data analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The study included 68 subjects (136 implants). No statistically significant differences were found between groups for any of the clinical outcomes measured. The mean change in MBL from loading to 12\u2009months was 0.04\u2009mm (SD\u2009=\u20090.39) for the modified hydrophilic implants and 0.07\u2009mm (SD\u2009=\u20090.22) for the conventional implants (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.658), with no significant differences between the groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Over a 12\u2010month period of functional loading, both implant surfaces demonstrated comparable performance regarding peri\u2010implant bone stability, safety, and clinical outcomes. Although a small but statistically significant difference between groups was observed in MBL changes from baseline to 12\u2009months (MD\u2009=\u20090.15\u2009mm), no significant differences were found in MBL changes from loading to 12\u2009months (primary outcome), ISQ, soft tissue healing, or peri\u2010implant health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.70071","type":"journal-article","created":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T04:36:17Z","timestamp":1762490177000},"page":"141-154","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical and Radiographic Performance of Two Distinct Sandblasted, Large\u2010Grit, Acid\u2010Etched Implant Surfaces: A Split\u2010Mouth Randomized Clinical Trial"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8074-8661","authenticated-orcid":false,"given":"Blanca","family":"V\u00edlchez","sequence":"first","affiliation":[{"name":"Postgraduate Clinic of Periodontology School of Dentistry, University Complutense of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1722-0889","authenticated-orcid":false,"given":"Leticia","family":"Caneiro","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Oral Surgery School of Dentistry University of Santiago de Compostela  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3242-7522","authenticated-orcid":false,"given":"Cristina","family":"Lima","sequence":"additional","affiliation":[{"name":"Postgraduate Clinic of Periodontology School of Dentistry, University Complutense of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3698-4772","authenticated-orcid":false,"given":"Ignacio","family":"Sanz\u2010S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Postgraduate Clinic of Periodontology School of Dentistry, University Complutense of Madrid  Madrid Spain"},{"name":"ETEP (Etiology and Therapy of Periodontal and Peri\u2010Implant Diseases) Research Group School of Dentistry, University Complutense of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2525-8529","authenticated-orcid":false,"given":"Eduardo","family":"Montero","sequence":"additional","affiliation":[{"name":"Postgraduate Clinic of Periodontology School of Dentistry, University Complutense of Madrid  Madrid Spain"},{"name":"ETEP (Etiology and Therapy of Periodontal and Peri\u2010Implant Diseases) Research Group School of Dentistry, University Complutense of Madrid  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