{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T10:27:26Z","timestamp":1793960846844,"version":"4.8.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100008401","name":"Stiftung Professor Dr. Max Clo\u00ebtta","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008401","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This preclinical study evaluated the influence of two defect morphologies on graft material displacement (GMD) during primary wound closure in horizontal bone augmentation (HBA). Secondary aims included assessing the effect of membrane stabilization and the role of local soft tissue characteristics on GMD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Standardized HBA procedures following guided bone regeneration principles were performed on fresh pig hemimandibles. Each mandible received two sequential HBAs, randomized for defect morphology\u2014partially contained (PCD) vs. contained (CD)\u2014and membrane stabilization with (+Pins) or without (\u2212Pins) four fixation pins. GMD was assessed using cone\u2010beam computed tomography and intraoral scanning by comparing graft dimensions before and after wound closure, at nine\u00a0levels from the implant platform and across nine delimited sections, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty HBA procedures were analyzed. A notable GMD was observed for both PCD and CD, with no significant differences between them. In contrast, membrane stabilization significantly reduced three\u2010dimensional GMD across all sections, with the most pronounced effect in the central\u2010crestal section (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). At the implant platform level, GMD was \u221215.8%\u2009\u00b1\u200925.6% with pins vs. \u221238.1%\u2009\u00b1\u200927.4% without pins (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Across all groups, GMD occurred in an apico\u2010lateral direction, with the greatest volume loss in the central\u2010crestal, mesial, and distal crestal sections. Soft tissue phenotype did not affect GMD (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009\u2265\u20090.240).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Defect morphology did not significantly influence the notable apico\u2010lateral GMD. However, membrane stabilization using pins effectively reduced graft displacement, minimizing movement during primary wound closure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.70072","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T04:38:17Z","timestamp":1762403897000},"page":"314-326","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Effect of Defect Morphology and Membrane Fixation on 3D Graft Material Displacement During Primary Wound Closure in Horizontal Bone Augmentation\u2014An Ex\u00a0Vivo Study"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2659-3505","authenticated-orcid":false,"given":"Clemens","family":"Raabe","sequence":"first","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum  Frankfurt am Main Germany"},{"name":"Department of Oral Surgery and Stomatology, School of Dental Medicine University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9243-1382","authenticated-orcid":false,"given":"Emilio A.","family":"Cafferata","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum  Frankfurt am Main Germany"},{"name":"Oral Peri\u2010Implant Research Group, School of Dentistry Universidad Cient\u00edfica del Sur  Lima Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8158-253X","authenticated-orcid":false,"given":"Wenjie","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8121-5246","authenticated-orcid":false,"given":"Katharina M.","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelam","family":"Lingwal","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1649-1882","authenticated-orcid":false,"given":"Ausra","family":"Ramanauskaite","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5515-227X","authenticated-orcid":false,"given":"Frank","family":"Schwarz","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9989-4483","authenticated-orcid":false,"given":"Emilio","family":"Couso\u2010Queiruga","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Stomatology, School of Dental Medicine University of Bern  Bern 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