{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T22:58:52Z","timestamp":1793228332046,"version":"4.5.0"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T00:00:00Z","timestamp":1771113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T00:00:00Z","timestamp":1771113600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002551","name":"Seoul National University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002551","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study evaluated the 5\u2010year survival of bone\u2010level, internal connection, sandblasted and acid\u2010etched (SA) implants and identified site\u2010 and patient\u2010related risk factors for implant failure in a multicenter cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A total of 3555 tapered bone\u2010level SA implants were placed between 2012 and 2018 at two university dental hospitals. The observation period spanned from placement to removal or the last follow\u2010up (final date: May 15, 2025). Survival outcomes were analyzed using Kaplan\u2013Meier estimates and Cox regression with shared frailty terms to adjust for clustering within patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The 5\u2010year cumulative survival rate was 98.8% at the implant level and 99.0% at the patient level. Tooth loss due to periodontitis significantly increased implant failure risk (adjusted HR 3.57, 95% CI: 1.49\u20138.54,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). Implants placed without guided bone regeneration (GBR) had a lower risk of failure than those with GBR (adjusted HR 0.42, 95% CI: 0.18\u20130.96,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04). Supportive periodontal therapy (SPT) compliance also influenced outcomes (adjusted HR 2.35, 95% CI: 1.32\u20134.18,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). Stratified analysis showed a marked survival benefit of regular SPT among patients with periodontitis\u2010related tooth loss (98.8% vs. 96.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Bone\u2010level internal connection SA implants demonstrated favorable long\u2010term survival. However, periodontitis\u2010related tooth loss, GBR, and SPT compliance significantly affected implant longevity, emphasizing individualized risk assessment and continuous maintenance care. The absence of longitudinal radiographic bone\u2010level data limits further evaluation of peri\u2010implant bone stability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.70103","type":"journal-article","created":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T13:10:11Z","timestamp":1771161011000},"page":"590-611","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Supportive Periodontal Therapy Improves Implant Survival in Patients With a History of Periodontitis: A Retrospective Multicenter Cohort Study of 3555 Implants"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4146-3119","authenticated-orcid":false,"given":"Dongseob","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Periodontology and Dental Research Institute, School of Dentistry Seoul National University  Seoul Republic of Korea"},{"name":"National Dental Care Center for Persons With Special Needs, Seoul National University Dental Hospital  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8578-1065","authenticated-orcid":false,"given":"Sungrak","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Dental Research Institute, School of Dentistry Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2737-1139","authenticated-orcid":false,"given":"Jin Young","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Dental Research Institute, School of Dentistry Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3014-792X","authenticated-orcid":false,"given":"Seung\u2010Ju","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Dental Research Institute, School of Dentistry Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5619-3847","authenticated-orcid":false,"given":"Yong\u2010Moo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Dental Research Institute, School of Dentistry Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9809-2630","authenticated-orcid":false,"given":"Ki\u2010Tae","family":"Koo","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Dental Research Institute, School 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