{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:16:20Z","timestamp":1790727380156,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T00:00:00Z","timestamp":1771113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T00:00:00Z","timestamp":1771113600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study assessed whether periodontitis stage and grade are associated with long\u2010term implant survival in periodontally compromised patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted among 362 periodontitis patients who received 1106 implants at the University Clinic M\u00fcnster, Germany, with a median follow\u2010up of 85.5\u2009months (range: 3.6\u2013236.4). Periodontitis stage and grade were assessed based on clinical and radiographic data at the first clinical visit. Kaplan\u2013Meier curves and Cox regression models were used to analyze implant survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 85 implants (7.69%) failed, with nearly half of these losses occurring within the first six months (failed osseointegration). Cumulative survival rates were 95.8% at 60\u2009months, 91.1% at 120\u2009months, and 82.6% at 180\u2009months. Grading, but not staging, was significantly associated with implant loss. Patients classified as grade C had a higher risk of implant loss at any given time during follow\u2010up than patients with grade A or B (hazard ratio\u2009=\u20092.78; 95% confidence interval: 1.18\u20136.54).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings demonstrate that periodontitis, particularly in terms of grading as defined by the current classification, is a significant risk factor for implant loss, even in patients undergoing periodontal therapy. Both clinicians and patients should consider these risk factors during treatment planning, as they can substantially impact implant survival. Nevertheless, dental implants remain a reliable and predictable therapeutic option, even for patients with severe periodontitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.70105","type":"journal-article","created":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T14:00:03Z","timestamp":1771164003000},"page":"623-629","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Long\u2010Term Implant Survival in Periodontitis"],"prefix":"10.1111","volume":"37","author":[{"given":"Almir","family":"Kashta","sequence":"first","affiliation":[{"name":"Clinic for Periodontology and Conservative Dentistry University of M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9391-6602","authenticated-orcid":false,"given":"Sebastian\u2010Edgar","family":"Baumeister","sequence":"additional","affiliation":[{"name":"Institute of Health Services Research in Dentistry University of M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Ehmke","sequence":"additional","affiliation":[{"name":"Clinic for Periodontology and Conservative Dentistry University of M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5273-7288","authenticated-orcid":false,"given":"Stefan Lars","family":"Reckelkamm","sequence":"additional","affiliation":[{"name":"Clinic for Periodontology and Conservative Dentistry University of M\u00fcnster  M\u00fcnster Germany"},{"name":"Institute of Health Services Research in Dentistry University of M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12013"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/insr.12214"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.10.1404"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.61872\/sdj-2024-02-08"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13828"},{"key":"e_1_2_11_7_1","first-page":"1","article-title":"Prevalence of Tooth Loss Among Older Adults: United States, 2015\u20132018","volume":"368","author":"Fleming E.","year":"2020","journal-title":"NCHS Data Brief"},{"issue":"3","key":"e_1_2_11_8_1","first-page":"613","article-title":"Retrospective Study of the Long\u2010Term Survival of 980 Implants Placed in a Periodontal Practice","volume":"25","author":"Garc\u00eda\u2010Bellosta S.","year":"2010","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2012.00457.x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-8-126"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13585"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.22-0196"},{"issue":"4","key":"e_1_2_11_13_1","first-page":"569","article-title":"Dental Implant Failure Rates and Associated Risk Factors","volume":"20","author":"Moy P. K.","year":"2005","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.13337"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0721"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67728-8"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.21-0012"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01416.x"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12408"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13104"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.11.008"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12101723"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.70105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/clr.70105","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.70105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T14:32:31Z","timestamp":1778250751000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/clr.70105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,15]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1111\/clr.70105"],"URL":"https:\/\/doi.org\/10.1111\/clr.70105","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,15]]},"assertion":[{"value":"2025-04-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}