{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:46:07Z","timestamp":1786117567319,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100011970","name":"International Team for Implantology","doi-asserted-by":"publisher","award":["1286_2018"],"award-info":[{"award-number":["1286_2018"]}],"id":[{"id":"10.13039\/501100011970","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This one\u2010year randomized clinical trial compared the effects of mandibular implant\u2010overdentures (IODs) on two two\u2010piece regular\u2010neck tissue\u2010level implants (Group A) or on four mini\u2010implants (Group B) with different loading protocols in edentulous patients concerning dental Patient\u2010Reported Outcomes (dPROs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>\n                      Seventy\u2010two participants were randomly assigned to Group A (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200935) for treatment with two standard implants (3.3\u2009mm diameter, conventional loading) with a stud\u2010type abutment, or to Group B (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200937) for treatment with four mini\u2010implants (2.4\u2009mm diameter, immediate loading) with a mini\u2010stud\u2010type abutment. Primary outcomes were measured using the General Oral Health Assessment Index (GOHAI), the 14\u2010item Oral Health Impact Profile (OHIP\u2010G14), and the Denture Satisfaction Index (DSI), at visit #1\u2014baseline (pre\u2010treatment), visit #2\u2014implant placement (immediate loading, Group B), visit #3\u20138\u201010\u2010week follow\u2010up (conventional loading, Group A; control visit, Group B), and visit #4\u20131\u2010year post\u2010placement. Data analysis included descriptive statistics, non\u2010parametric comparison tests, effect\u2010size measures, and multiple regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty\u2010two participants completed the 1\u2010year follow\u2010up (Group A\u2009=\u200932; Group B\u2009=\u200930). Significantly improved dPROs were observed for both treatments after 1 year, compared with baseline (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), with similar effects in the two Groups. In the mini\u2010implant group, higher improvement in satisfaction was observed after implant placement and immediate loading, compared to Group A (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Significant improvements in satisfaction and Oral Health Related Quality of Life\u00a0were observed after 1 year, and benefits were observed earlier for mini\u2010implants using immediate loading. Overall, findings support the use of four immediately loaded mini\u2010implants in the mandible as a suitable treatment alternative for edentulous patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p>\n                      ClinicalTrials.Gov ID: NCT03837158.\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/clinicaltrials.gov\/study\/NCT03837158\">https:\/\/clinicaltrials.gov\/study\/NCT03837158<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.70143","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T04:17:32Z","timestamp":1780373852000},"page":"983-993","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Mandibular Overdentures on Four Immediately Loaded Mini\u2010Implants Versus Two\u2010Delayed Loaded Regular Implants: 1\u2010Year, Two\u2010Center RCT on Patient\u2010Reported Outcomes"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9700-5534","authenticated-orcid":false,"given":"Martin","family":"Schimmel","sequence":"first","affiliation":[{"name":"Department of Reconstructive Dentistry and Gerodontology, School of Dental Medicine University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6812-4849","authenticated-orcid":false,"given":"Cl\u00e1udio Rodrigues","family":"Leles","sequence":"additional","affiliation":[{"name":"Department of Reconstructive Dentistry and Gerodontology, School of Dental Medicine University of Bern  Bern Switzerland"},{"name":"School of Dentistry Federal University of Goias  Goiania Goias Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8025-819X","authenticated-orcid":false,"given":"Nicole","family":"Schenk","sequence":"additional","affiliation":[{"name":"Department of Reconstructive Dentistry and Gerodontology, School of Dental Medicine University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7597-6863","authenticated-orcid":false,"given":"Simone F. M.","family":"Janner","sequence":"additional","affiliation":[{"name":"Surgery Center ZIKO Bern  Bern Switzerland"},{"name":"Department of Oral Surgery and Stomatology School of Dental Medicine, University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beat","family":"Wallkamm","sequence":"additional","affiliation":[{"name":"Division of Periodontology School of Dental Medicine, University of Geneva  Geneva Switzerland"},{"name":"Private Practice  Langenthal Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3206-5266","authenticated-orcid":false,"given":"Val\u00e9rie G. A.","family":"Suter","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Stomatology School of Dental Medicine, University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1047-5571","authenticated-orcid":false,"given":"Samir","family":"Abou\u2010Ayash","sequence":"additional","affiliation":[{"name":"Department of Prosthetic Dentistry and Material Science University Medical Center of the Johannes Gutenberg University Mainz  Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2659-3505","authenticated-orcid":false,"given":"Clemens","family":"Raabe","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Stomatology School of Dental Medicine, University of Bern  Bern Switzerland"},{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,1]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.14065"},{"issue":"5","key":"e_1_2_11_3_1","first-page":"446","article-title":"A Modified Short Version of the Oral Health Impact Profile for Assessing Health\u2010Related Quality of Life in Edentulous Adults","volume":"15","author":"Allen F.","year":"2002","journal-title":"International Journal of Prosthodontics"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477\u20107525\u20101\u201040"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100528.1998.tb01978.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ma10101197"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20103913(13)60035\u20109"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2024.105267"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.14102"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515601959"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136\u2010020\u201002709\u2010w"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13444"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12822"},{"issue":"4","key":"e_1_2_11_14_1","first-page":"601","article-title":"The McGill Consensus Statement on Overdentures. 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