{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T11:18:25Z","timestamp":1789384705010,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To quantify immediate graft displacement following tension\u2010free flap closure in non\u2010contained alveolar ridge defects regenerated using three membrane fixation strategies in an ex\u00a0vivo human model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Eighteen sites from six fresh cadaveric heads with non\u2010contained defects underwent horizontal guided bone regeneration using deproteinized bovine bone mineral and a collagen membrane stabilized by no fixation (NF), periosteal sutures (PS), or titanium fixation pins (FP). Techniques were applied sequentially. Cone\u2010beam CT scans were obtained at baseline, post\u2010grafting, and after passive closure. Linear ridge width was measured at 12 standardized positions, and graft volumes were segmented from STL reconstructions. Mixed\u2010effects multilevel linear regression assessed width changes, while Friedman and paired Wilcoxon tests evaluated volumetric outcomes, with Tukey\u2010adjusted contrasts for intergroup comparisons.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fixation pins virtually eliminated graft displacement (\u22126.7\u2009\u00b1\u200987\u2009mm\n                      <jats:sup>3<\/jats:sup>\n                      ) and achieved the highest stability (81.2%\u2009\u00b1\u20098.2%), significantly outperforming periosteal sutures (\u221296\u2009\u00b1\u2009165\u2009mm\n                      <jats:sup>3<\/jats:sup>\n                      ; 70.1%\u2009\u00b1\u20094.5%) and no fixation (\u2212247\u2009\u00b1\u2009150\u2009mm\n                      <jats:sup>3<\/jats:sup>\n                      ; 44.4%\u2009\u00b1\u200917.9%) (loss\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.030; stability\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). Ridge collapse was greatest with no fixation (\u22121.37\u2009\u00b1\u20090.85\u2009mm) compared with PS (\u22120.40\u2009\u00b1\u20090.62\u2009mm) and FP (\u22120.28\u2009\u00b1\u20090.61\u2009mm). After adjustment, PS and FP reduced collapse by 0.96\u2009mm (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012) and 1.11\u2009mm (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004), respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Even after passive flap release and tension\u2010free closure, membrane fixation, particularly with titanium pins, provides superior resistance to graft displacement in non\u2010contained defects, while unfixed membranes allow substantial graft loss and are therefore not recommended in non\u2010contained defects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.70146","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T11:41:59Z","timestamp":1781264519000},"page":"1020-1032","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Collagen Membrane Fixation Technique Affects Its Space Maintenance Capacity After Flap Closure: An Ex\u00a0Vivo Analysis"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5067-7317","authenticated-orcid":false,"given":"Muhammad H. A.","family":"Saleh","sequence":"first","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1080-6285","authenticated-orcid":false,"given":"Javier","family":"Calatrava","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"},{"name":"Section of Graduate Periodontology, Faculty of Odontology University Complutense  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5516-9810","authenticated-orcid":false,"given":"Nataly","family":"Zambrana","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3158-6477","authenticated-orcid":false,"given":"Lucrezia","family":"Parma\u2010Benfenati","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6581-2104","authenticated-orcid":false,"given":"Hamoun","family":"Sabri","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9368-4047","authenticated-orcid":false,"given":"Istvan","family":"Urban","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"},{"name":"Department of Oral Medicine, Infection Control and Immunity Harvard University  Boston Massachusetts USA"},{"name":"Department of Prosthetic Dentistry University of Szeged  Szeged Hungary"},{"name":"Urban Regeneration Institute  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4238-1799","authenticated-orcid":false,"given":"Hom\u2010Lay","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13583"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01703.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/ijod\/2617319"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12539"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.1208"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.11.1743"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.4861"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1155\/crid\/2659893"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.14433"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.22917"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13084"},{"key":"e_1_2_11_13_1","first-page":"4","article-title":"Comparison Between Sandwich Bone Augmentation and Allogenic Block Graft for Vertical Ridge Augmentation in the Posterior Mandible","volume":"24","author":"Leong D. 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