{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T06:03:24Z","timestamp":1789452204718,"version":"build-2803163510"},"reference-count":51,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:00:00Z","timestamp":1789344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:00:00Z","timestamp":1789344000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271004"],"award-info":[{"award-number":["82271004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82471007"],"award-info":[{"award-number":["82471007"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This retrospective study analyzed the clinical data of 27 patients with severe tooth agenesis who underwent zygomatic implants (ZIs) over the past 15\u2009years, with an aim of evaluating the efficacy and safety of ZIs in patients with severe oligodontia and anodontia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Patients who were diagnosed with severe oligodontia or anodontia and treated with ZI were included. All the patients received comprehensive preoperative assessments, including radiographic imaging, genetic testing, and multidisciplinary consultations to develop customized treatment plans. The treatment strategies primarily involved extensive bone grafting combined with multiple conventional implants (CIs) and a single ZI approach or the Quad Zygoma approach. Postoperative rehabilitation involved immediate or delayed loading with provisional prostheses, followed by definitive full\u2010arch implant\u2010supported restorations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010seven patients with 20 patients exhibiting syndromes, aged 18\u201337\u2009years (mean age 22.63), were enrolled. A total of 85 ZIs and 42 CIs were placed in the maxilla. All the ZIs achieved successful osseointegration, yielding an early survival rate of 100%. The crude survival rates of ZIs and CIs were 98.5% (84\/85) and 76.19% (32\/42) at the implant level and 96.3% (26\/27) and 64.71% (11\/17) at the patient level, respectively, with a mean follow\u2010up of 55.07\u2009months (range: 13.27\u2013179.2\u2009months). The main complications associated with ZIs included maxillary sinus opacification and peri\u2010implant soft\u2010tissue recession.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ZIs could be a treatment option for patients with severe oligodontia and anodontia. This study may support the feasibility and favorable outcomes of ZIs in the management of severe tooth agenesis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.70174","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T05:15:27Z","timestamp":1789449327000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Retrospective Evaluation of Zygomatic Implant Therapy in Patients With Severe Tooth Agenesis and Maxillary Deficiencies: Clinical Outcomes and Safety up to 15 Years of Follow\u2010Up"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0066-5470","authenticated-orcid":false,"given":"Baoxin","family":"Tao","sequence":"first","affiliation":[{"name":"Department of Second Dental Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4511-686X","authenticated-orcid":false,"given":"Feng","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Surgery, Faculty of Dentistry The University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihan","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Second Dental Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8352-6256","authenticated-orcid":false,"given":"Yiqun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Second Dental Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9378325"},{"key":"e_1_2_11_3_1","volume-title":"Consensus Report of Session IV","author":"Albrektsson T.","year":"1994"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40729\u2010023\u201000489\u20109"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12038"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13073"},{"issue":"3","key":"e_1_2_11_7_1","first-page":"398","article-title":"Analysis of 356 Pterygomaxillary Implants in Edentulous Arches for Fixed Prosthesis Anchorage","volume":"14","author":"Balshi T. 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