{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:00:37Z","timestamp":1790312437276,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oral Implants Res"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the long\u2010term impact of single implant\u2010supported crowns on the health status of adjacent natural teeth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Clinical and radiographic data from 456 subjects with single implants were analyzed. Complication rates (caries, new restorations, tooth loss) of adjacent teeth were compared against three intra\u2010patient control groups (other quadrants) using data at restoration delivery as the baseline. Multivariate models assessed risk over short\u2010term (1\u20135\u2009years) and long\u2010term (5\u201315\u2009years) periods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean follow\u2010ups were 3.88\u2009\u00b1\u20091.75\u2009years for the short\u2010term (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009456) and 8.90\u2009\u00b1\u20092.10\u2009years for the long\u2010term (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009180) cohorts. Adjacent teeth showed significantly higher overall complication rates compared to all control groups in both the short\u2010term (8.0% vs. 2.2%\u20132.7%; ORs: 2.92\u20133.65) and long\u2010term follow\u2010ups (15.0% vs. 6.4%\u20137.8%; ORs: 2.16\u20132.57). A clear positional dichotomy emerged: mesial teeth showed pronounced short\u2010term caries susceptibility, while distal teeth drove a short\u2010term risk of tooth loss. Restoration needs remained consistently elevated. Bone\u2010level implants (short\u2010term OR: 0.44; long\u2010term OR: 0.38), narrow\u2010diameter implants (OR: 0.23), and pre\u2010existing orthodontic alignment (OR: 0.20) were associated with a lower incidence of complications, whereas patient\u2010level factors such as bruxism (OR: 5.78) and male gender (OR: 10.88) correlated with increased complication rates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Single implant\u2010supported restorations significantly elevate the incidence of caries, new restorations, and tooth loss in adjacent teeth relative to controls. While adjacent tooth loss is predominantly an acute short\u2010term risk localized to distal teeth, susceptibility to carious lesions and restorative interventions represents a persistent, long\u2010term morbidity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.70180","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:40:34Z","timestamp":1790311234000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Long\u2010Term Impact of Single Implant\u2010Supported Crowns on Adjacent Natural Teeth: A Retrospective Longitudinal Study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8684-4666","authenticated-orcid":false,"given":"Jinlong","family":"Shao","sequence":"first","affiliation":[{"name":"Department of Periodontology, School and Hospital of Stomatology Cheeloo College of Medicine, Shandong University, &amp; Shandong Key Laboratory of Oral Diseases &amp; Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration &amp; Shandong Provincial Clinical Research Center for Oral Diseases  Jinan Shandong China"},{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6294-4048","authenticated-orcid":false,"given":"Qasim Omer","family":"Butt","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9438-3784","authenticated-orcid":false,"given":"Chen\u2010Lin","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanyang","family":"Man","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School and Hospital of Stomatology Cheeloo College of Medicine, Shandong University, &amp; Shandong Key Laboratory of Oral Diseases &amp; Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration &amp; Shandong Provincial Clinical Research Center for Oral Diseases  Jinan Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hammad","family":"Chaudhry","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7567-0041","authenticated-orcid":false,"given":"Maaham Khan","family":"Lodhi","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4238-1799","authenticated-orcid":false,"given":"Hom\u2010Lay","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"issue":"1","key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0011-8532(22)02100-0","article-title":"Osseointegrated Dental Implants","volume":"30","author":"Albrektsson T.","year":"1986","journal-title":"Dental Clinics of North 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