{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:01:09Z","timestamp":1791216069202,"version":"4.1.0"},"reference-count":57,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":124,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI082548"],"award-info":[{"award-number":["AI082548"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Microbiol"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1111\/cmi.12444","type":"journal-article","created":{"date-parts":[[2015,4,8]],"date-time":"2015-04-08T00:42:43Z","timestamp":1428453763000},"page":"796-801","source":"Crossref","is-referenced-by-count":32,"title":["The metabolic control of schistosome egg production"],"prefix":"10.1155","volume":"17","author":[{"given":"Edward J.","family":"Pearce","sequence":"first","affiliation":[{"name":"Department of Pathology and Immunology; Washington University School of Medicine; St. Louis MO 63110-1093 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley Ching-Cheng","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pathology and Immunology; Washington University School of Medicine; St. Louis MO 63110-1093 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,4,30]]},"reference":[{"key":"10.1111\/cmi.12444-BIB0001|cmi12444-cit-0001","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1590\/S0074-02762009000400013","article-title":"High fat diet has a prominent effect upon the course of chronic schistosomiasis mansoni in mice","volume":"104","author":"Alencar","year":"2009","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"10.1111\/cmi.12444-BIB0002|cmi12444-cit-0002","doi-asserted-by":"crossref","first-page":"605","DOI":"10.2307\/3276242","article-title":"Mating behavior and development of schistosomes in the mouse","volume":"51","author":"Armstrong","year":"1965","journal-title":"J Parasitol"},{"key":"10.1111\/cmi.12444-BIB0003|cmi12444-cit-0003","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1146\/annurev-ento-112408-085356","article-title":"Insect fat body: energy, metabolism, and regulation","volume":"55","author":"Arrese","year":"2010","journal-title":"Annu Rev Entomol"},{"key":"10.1111\/cmi.12444-BIB0004|cmi12444-cit-0004","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1039\/c0mb00262c","article-title":"Metabonomic investigation of human Schistosoma mansoni infection","volume":"7","author":"Balog","year":"2011","journal-title":"Mol Biosyst"},{"key":"10.1111\/cmi.12444-BIB0005|cmi12444-cit-0005","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-349-86119-4","volume-title":"Biochemistry of Parasitic Helminths","author":"Barrett","year":"1981"},{"key":"10.1111\/cmi.12444-BIB0006|cmi12444-cit-0006","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1017\/S003118200900568X","article-title":"Forty years of helminth biochemistry","volume":"136","author":"Barrett","year":"2009","journal-title":"Parasitology"},{"key":"10.1111\/cmi.12444-BIB0007|cmi12444-cit-0007","doi-asserted-by":"crossref","first-page":"179","DOI":"10.2307\/3280632","article-title":"Cultivation of Schistosoma mansoni in vitro. I. Establishment of cultures from cercariae and development until pairing","volume":"67","author":"Basch","year":"1981","journal-title":"J Parasitol"},{"issue":"Part 2","key":"10.1111\/cmi.12444-BIB0008|cmi12444-cit-0008","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1017\/S0031182000001372","article-title":"Intergeneric reproductive stimulation and parthenogenesis in Schistosoma mansoni","volume":"89","author":"Basch","year":"1984","journal-title":"Parasitology"},{"key":"10.1111\/cmi.12444-BIB0009|cmi12444-cit-0009","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1152\/physrev.1990.70.2.567","article-title":"Energy contributions of volatile fatty acids from the gastrointestinal tract of various species","volume":"70","author":"Bergman","year":"1990","journal-title":"Physiol Rev"},{"key":"10.1111\/cmi.12444-BIB0010|cmi12444-cit-0010","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/nature08160","article-title":"The genome of the blood fluke Schistosoma mansoni","volume":"460","author":"Berriman","year":"2009","journal-title":"Nature"},{"key":"10.1111\/cmi.12444-BIB0011|cmi12444-cit-0011","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0166-6851(97)00091-1","article-title":"The incorporation, modification and turnover of fatty acids in adult Schistosoma mansoni","volume":"88","author":"Brouwers","year":"1997","journal-title":"Mol Biochem Parasitol"},{"key":"10.1111\/cmi.12444-BIB0012|cmi12444-cit-0012","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1038\/nrmicro801","article-title":"Schistosomiasis","volume":"2","author":"Chitsulo","year":"2004","journal-title":"Nat Rev Microbiol"},{"key":"10.1111\/cmi.12444-BIB0013|cmi12444-cit-0013","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0009-8981(81)90359-4","article-title":"Volatile fatty acids inhuman peripheral and portal blood: quantitative determination by vacuum distillation and gas chromatography","volume":"110","author":"Dankert","year":"1981","journal-title":"Clin Chim Acta"},{"issue":"Part 3","key":"10.1111\/cmi.12444-BIB0014|cmi12444-cit-0014","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1017\/S0031182000054731","article-title":"Schistosoma mansoni: DNA synthesis in males and females from mixed and single-sex infections","volume":"88","author":"Den Hollander","year":"1984","journal-title":"Parasitology"},{"key":"10.1111\/cmi.12444-BIB0015|cmi12444-cit-0015","doi-asserted-by":"crossref","first-page":"e39","DOI":"10.1016\/j.ijid.2007.10.007","article-title":"Saposin-like proteins are expressed in the gastrodermis of Schistosoma mansoni and are immunogenic in natural infections","volume":"12","author":"Don","year":"2008","journal-title":"Int J Infect Dis"},{"key":"10.1111\/cmi.12444-BIB0016|cmi12444-cit-0016","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1017\/S0031182000046394","article-title":"A comparative study of the reproductive system of mature, immature and \u2018unisexual\u2019 female Schistosoma mansoni","volume":"67","author":"Erasmus","year":"1973","journal-title":"Parasitology"},{"key":"10.1111\/cmi.12444-BIB0017|cmi12444-cit-0017","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1017\/S0031182000044838","article-title":"A comparative study of the vitelline cell in Schistosoma mansoni, S. haematobium, S. japonicum and S. mattheei","volume":"84","author":"Erasmus","year":"1982","journal-title":"Parasitology"},{"key":"10.1111\/cmi.12444-BIB0018|cmi12444-cit-0018","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.aca.2014.06.013","article-title":"Screening the life cycle of Schistosoma mansoni using high-resolution mass spectrometry","volume":"845","author":"Ferreira","year":"2014a","journal-title":"Anal Chim Acta"},{"key":"10.1111\/cmi.12444-BIB0019|cmi12444-cit-0019","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1002\/jms.3308","article-title":"Mass spectrometry imaging: a new vision in differentiating Schistosoma mansoni strains","volume":"49","author":"Ferreira","year":"2014b","journal-title":"J Mass Spectrom"},{"key":"10.1111\/cmi.12444-BIB0020|cmi12444-cit-0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.0030052","article-title":"TGF-b signaling controls embryo development in the parasitic flatworm Schistosoma mansoni","author":"Freitas","year":"2007","journal-title":"PLoS Pathog"},{"key":"10.1111\/cmi.12444-BIB0021|cmi12444-cit-0021","doi-asserted-by":"crossref","first-page":"e1509","DOI":"10.1371\/journal.pntd.0001509","article-title":"Cell death and reproductive regression in female Schistosoma mansoni","volume":"6","author":"Galanti","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1111\/cmi.12444-BIB0022|cmi12444-cit-0022","doi-asserted-by":"crossref","first-page":"R545","DOI":"10.1016\/j.cub.2004.07.006","article-title":"Schistosoma","volume":"14","author":"Grevelding","year":"2004","journal-title":"Curr Biol"},{"key":"10.1111\/cmi.12444-BIB0023|cmi12444-cit-0023","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1242\/jcs.037630","article-title":"Lipid droplets at a glance","volume":"122","author":"Guo","year":"2009","journal-title":"J Cell Sci"},{"key":"10.1111\/cmi.12444-BIB0024|cmi12444-cit-0024","doi-asserted-by":"crossref","first-page":"481","DOI":"10.2307\/3282125","article-title":"The role of Schistosoma mansoni males in feeding and development of female worms","volume":"73","author":"Gupta","year":"1987","journal-title":"J Parasitol"},{"key":"10.1111\/cmi.12444-BIB0025|cmi12444-cit-0025","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1038\/nm.2439","article-title":"ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1","volume":"17","author":"Haemmerle","year":"2011","journal-title":"Nat Med"},{"issue":"Part 2","key":"10.1111\/cmi.12444-BIB0026|cmi12444-cit-0026","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1017\/S0031182000062570","article-title":"The transition from an aerobic to an anaerobic energy metabolism in transforming Schistosoma mansoni cercariae occurs exclusively in the head","volume":"102","author":"Horemans","year":"1991","journal-title":"Parasitology"},{"key":"10.1111\/cmi.12444-BIB0027|cmi12444-cit-0027","doi-asserted-by":"crossref","first-page":"e1002996","DOI":"10.1371\/journal.ppat.1002996","article-title":"Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni","volume":"8","author":"Huang","year":"2012","journal-title":"PLoS Pathog"},{"key":"10.1111\/cmi.12444-BIB0028|cmi12444-cit-0028","volume-title":"The Invertebrates, Vol. 2, Platyhelminthes and Rhyncocoela","author":"Hyman","year":"1951"},{"key":"10.1111\/cmi.12444-BIB0029|cmi12444-cit-0029","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1177\/1742395307084407","article-title":"The unacknowledged impact of chronic schistosomiasis","volume":"4","author":"King","year":"2008","journal-title":"Chronic Illn"},{"key":"10.1111\/cmi.12444-BIB0030|cmi12444-cit-0030","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1046\/j.1440-169X.2002.00667.x","article-title":"Quantification of DNA synthesis in multicellular organisms by a combined DAPI and BrdU technique","volume":"44","author":"Knobloch","year":"2002","journal-title":"Dev Growth Differ"},{"key":"10.1111\/cmi.12444-BIB0031|cmi12444-cit-0031","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.exppara.2007.04.006","article-title":"Tyrosine kinase and cooperative TGFbeta signaling in the reproductive organs of Schistosoma mansoni","volume":"117","author":"Knobloch","year":"2007","journal-title":"Exp Parasitol"},{"key":"10.1111\/cmi.12444-BIB0032|cmi12444-cit-0032","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S1471-4922(01)01893-1","article-title":"Schistosome male-female interaction: induction of germ-cell differentiation","volume":"17","author":"Kunz","year":"2001","journal-title":"Trends Parasitol"},{"key":"10.1111\/cmi.12444-BIB0033|cmi12444-cit-0033","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1645\/0022-3395(2002)088[0003:PASASA]2.0.CO;2","article-title":"Presidential address. Sex and schistosomes: an interesting biological interplay with control implications","volume":"88","author":"LoVerde","year":"2002","journal-title":"J Parasitol"},{"key":"10.1111\/cmi.12444-BIB0034|cmi12444-cit-0034","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.mib.2009.06.005","article-title":"Signal transduction regulates schistosome reproductive biology","volume":"12","author":"LoVerde","year":"2009","journal-title":"Curr Opin Microbiol"},{"key":"10.1111\/cmi.12444-BIB0035|cmi12444-cit-0035","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0005-2760(70)90170-0","article-title":"Lipid metabolism in the parasitic and free-living flatworms, Schistosoma mansoni and Dugesia dorotocephala","volume":"210","author":"Meyer","year":"1970","journal-title":"Biochim Biophys Acta"},{"key":"10.1111\/cmi.12444-BIB0036|cmi12444-cit-0036","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/0014-4894(69)90052-6","article-title":"Mating of Schistosoma mansoni in vitro","volume":"25","author":"Michaels","year":"1969","journal-title":"Exp Parasitol"},{"key":"10.1111\/cmi.12444-BIB0037|cmi12444-cit-0037","doi-asserted-by":"crossref","first-page":"921","DOI":"10.2307\/3277120","article-title":"Evolution and characteristics of Schistosoma mansoni eggs laid in vitro","volume":"54","author":"Michaels","year":"1968","journal-title":"J Parasitol"},{"key":"10.1111\/cmi.12444-BIB0038|cmi12444-cit-0038","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.exppara.2006.09.006","article-title":"Long-term feeding a high-fat diet causes histological and parasitological effects on murine schistosomiasis mansoni outcome","volume":"115","author":"Neves","year":"2007","journal-title":"Exp Parasitol"},{"key":"10.1111\/cmi.12444-BIB0039|cmi12444-cit-0039","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0166-6851(85)90080-5","article-title":"The energy production of the adult Schistosoma mansoni is for a large part aerobic","volume":"16","author":"Oordt","year":"1985","journal-title":"Mol Biochem Parasitol"},{"key":"10.1111\/cmi.12444-BIB0040|cmi12444-cit-0040","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.cmet.2009.01.009","article-title":"Drosophila HNF4 regulates lipid mobilization and beta-oxidation","volume":"9","author":"Palanker","year":"2009","journal-title":"Cell Metab"},{"key":"10.1111\/cmi.12444-BIB0041|cmi12444-cit-0041","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nri843","article-title":"The immunobiology of schistosomiasis","volume":"2","author":"Pearce","year":"2002","journal-title":"Nat Rev Immunol"},{"key":"10.1111\/cmi.12444-BIB0042|cmi12444-cit-0042","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.coi.2010.01.018","article-title":"Metabolism in T cell activation and differentiation","volume":"22","author":"Pearce","year":"2010","journal-title":"Curr Opin Immunol"},{"key":"10.1111\/cmi.12444-BIB0043|cmi12444-cit-0043","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ydbio.2009.09.015","article-title":"Cell death and tissue remodeling in planarian regeneration","volume":"338","author":"Pellettieri","year":"2010","journal-title":"Dev Biol"},{"key":"10.1111\/cmi.12444-BIB0044|cmi12444-cit-0044","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1161\/CIRCRESAHA.110.226860","article-title":"The PPAR-RXR transcriptional complex in the vasculature: energy in the balance","volume":"108","author":"Plutzky","year":"2011","journal-title":"Circ Res"},{"key":"10.1111\/cmi.12444-BIB0045|cmi12444-cit-0045","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/jez.1402320117","article-title":"Reproductive development of female Schistosoma mansoni (Digenea: Schistosomatidae) following bisexual pairing of worms and worm segments","volume":"232","author":"Popiel","year":"1984a","journal-title":"J Exp Zool"},{"key":"10.1111\/cmi.12444-BIB0046|cmi12444-cit-0046","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0020-7519(84)90047-X","article-title":"The morphology and reproductive status of female Schistosoma mansoni following separation from male worms","volume":"14","author":"Popiel","year":"1984b","journal-title":"Int J Parasitol"},{"key":"10.1111\/cmi.12444-BIB0047|cmi12444-cit-0047","doi-asserted-by":"crossref","first-page":"e1002820","DOI":"10.1371\/journal.ppat.1002820","article-title":"Germline transgenesis and insertional mutagenesis in Schistosoma mansoni mediated by murine leukemia virus","volume":"8","author":"Rinaldi","year":"2012","journal-title":"PLoS Pathog"},{"key":"10.1111\/cmi.12444-BIB0048|cmi12444-cit-0048","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0166-6851(80)90039-0","article-title":"The incorporation and utilization of radiolabelled lipids by adult Schistosoma mansoni in vitro","volume":"1","author":"Rumjanek","year":"1980","journal-title":"Mol Biochem Parasitol"},{"key":"10.1111\/cmi.12444-BIB0049|cmi12444-cit-0049","doi-asserted-by":"crossref","first-page":"385","DOI":"10.2307\/3279308","article-title":"Aerobic and anaerobic carbohydrate metabolism and egg production of Schistosoma mansoni in vitro","volume":"61","author":"Schiller","year":"1975","journal-title":"J Parasitol"},{"key":"10.1111\/cmi.12444-BIB0050|cmi12444-cit-0050","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1017\/S0022149X00010117","article-title":"Schistosoma mansoni: vitelline gland development in females from single sex infections","volume":"61","author":"Shaw","year":"1987","journal-title":"J Helminthol"},{"key":"10.1111\/cmi.12444-BIB0051|cmi12444-cit-0051","doi-asserted-by":"crossref","first-page":"e1004246","DOI":"10.1371\/journal.ppat.1004246","article-title":"Schistosome feeding and regurgitation","volume":"10","author":"Skelly","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.1111\/cmi.12444-BIB0052|cmi12444-cit-0052","doi-asserted-by":"crossref","first-page":"12676","DOI":"10.1073\/pnas.0404878101","article-title":"Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification","volume":"101","author":"Wang","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1111\/cmi.12444-BIB0053|cmi12444-cit-0053","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1126\/science.124.3215.269","article-title":"On respiratory impairment in cancer cells","volume":"124","author":"Warburg","year":"1956","journal-title":"Science"},{"key":"10.1111\/cmi.12444-BIB0054|cmi12444-cit-0054","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.exppara.2008.07.005","article-title":"Schistosoma mansoni: identification of SmNR4A, a member of nuclear receptor subfamily 4","volume":"120","author":"Wu","year":"2008","journal-title":"Exp Parasitol"},{"key":"10.1111\/cmi.12444-BIB0055|cmi12444-cit-0055","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.mce.2010.06.011","article-title":"Nuclear hormone receptors in parasitic helminths","volume":"334","author":"Wu","year":"2011","journal-title":"Mol Cell Endocrinol"},{"key":"10.1111\/cmi.12444-BIB0056|cmi12444-cit-0056","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0166-6851(82)90018-4","article-title":"Major phospholipids and phosphatidylcholine synthesis in adult Schistosoma mansoni","volume":"5","author":"Young","year":"1982","journal-title":"Mol Biochem Parasitol"},{"key":"10.1111\/cmi.12444-BIB0057|cmi12444-cit-0057","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.cmet.2011.12.018","article-title":"FAT SIGNALS-lipases and lipolysis in lipid metabolism and signaling","volume":"15","author":"Zechner","year":"2012","journal-title":"Cell Metab"}],"container-title":["Cellular Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcmi.12444","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/cmi.12444\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T11:14:22Z","timestamp":1651662862000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cmi.12444"}},"subtitle":["The metabolic control of schistosome egg production"],"short-title":[],"issued":{"date-parts":[[2015,4,30]]},"references-count":57,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"URL":"https:\/\/doi.org\/10.1111\/cmi.12444","relation":{},"ISSN":["1462-5814"],"issn-type":[{"value":"1462-5814","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4,30]]}}}