{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:14:43Z","timestamp":1790705683290,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,17]],"date-time":"2017-11-17T00:00:00Z","timestamp":1510876800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,11,17]],"date-time":"2017-11-17T00:00:00Z","timestamp":1510876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003323","name":"Agence Nationale de Recherches sur le Sida et les H\u00e9patites Virales","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003323","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Gilead Sciences International Research Scholars Program in Liver Disease"},{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["31003A-156030"],"award-info":[{"award-number":["31003A-156030"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cellular Microbiology"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1111\/cmi.12804","type":"journal-article","created":{"date-parts":[[2017,11,7]],"date-time":"2017-11-07T15:36:37Z","timestamp":1510068997000},"page":"e12804","source":"Crossref","is-referenced-by-count":40,"title":["Identification of GBF1 as a cellular factor required for hepatitis E virus RNA replication"],"prefix":"10.1155","volume":"20","author":[{"given":"Rayan","family":"Farhat","sequence":"first","affiliation":[{"name":"Pasteur Institute of Lille, U1019-UMR 8204-CIIL- Center for Infection and Immunity of Lille; University of Lille, CNRS, INSERM, CHU Lille; Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maliki","family":"Ankavay","sequence":"additional","affiliation":[{"name":"Pasteur Institute of Lille, U1019-UMR 8204-CIIL- Center for Infection and Immunity of Lille; University of Lille, CNRS, INSERM, CHU Lille; Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadjet","family":"Lebsir","sequence":"additional","affiliation":[{"name":"Pasteur Institute of Lille, U1019-UMR 8204-CIIL- Center for Infection and Immunity of Lille; University of Lille, CNRS, INSERM, CHU Lille; Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Gouttenoire","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois; University of Lausanne; Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0843-145X","authenticated-orcid":false,"given":"Catherine L.","family":"Jackson","sequence":"additional","affiliation":[{"name":"Institut Jacques Monod, CNRS UMR 7592; Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9; Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Czeslaw","family":"Wychowski","sequence":"additional","affiliation":[{"name":"Pasteur Institute of Lille, U1019-UMR 8204-CIIL- Center for Infection and Immunity of Lille; University of Lille, CNRS, INSERM, CHU Lille; Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darius","family":"Moradpour","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois; University of Lausanne; Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Dubuisson","sequence":"additional","affiliation":[{"name":"Pasteur Institute of Lille, U1019-UMR 8204-CIIL- Center for Infection and Immunity of Lille; University of Lille, CNRS, INSERM, CHU Lille; Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0788-9271","authenticated-orcid":false,"given":"Yves","family":"Rouill\u00e9","sequence":"additional","affiliation":[{"name":"Pasteur Institute of Lille, U1019-UMR 8204-CIIL- Center for Infection and Immunity of Lille; University of Lille, CNRS, INSERM, CHU Lille; Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2136-5178","authenticated-orcid":false,"given":"Laurence","family":"Cocquerel","sequence":"additional","affiliation":[{"name":"Pasteur Institute of Lille, U1019-UMR 8204-CIIL- Center for Infection and Immunity of Lille; University of Lille, CNRS, INSERM, CHU Lille; Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,17]]},"reference":[{"key":"10.1111\/cmi.12804-BIB0001|cmi12804-cit-0002","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1128\/JVI.01820-06","article-title":"Hijacking components of the cellular secretory pathway for replication of poliovirus RNA","volume":"81","author":"Belov","year":"2006","journal-title":"Journal of Virology"},{"key":"10.1111\/cmi.12804-BIB0002|cmi12804-cit-0003","doi-asserted-by":"crossref","first-page":"e1000216","DOI":"10.1371\/journal.ppat.1000216","article-title":"A critical role of a cellular membrane traffic protein in poliovirus RNA replication","volume":"4","author":"Belov","year":"2008","journal-title":"PLoS Pathogens"},{"key":"10.1111\/cmi.12804-BIB0003|cmi12804-cit-0004","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1111\/j.1462-5822.2010.01482.x","article-title":"Poliovirus replication requires the N-terminus but not the catalytic Sec7 domain of ArfGEF GBF1","volume":"12","author":"Belov","year":"2010","journal-title":"Cellular Microbiology"},{"key":"10.1111\/cmi.12804-BIB0004|cmi12804-cit-0005","doi-asserted-by":"crossref","first-page":"13001","DOI":"10.1128\/JVI.76.24.13001-13014.2002","article-title":"Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication","volume":"76","author":"Blight","year":"2002","journal-title":"Journal of Virology"},{"key":"10.1111\/cmi.12804-BIB0005|cmi12804-cit-0006","doi-asserted-by":"crossref","first-page":"2836","DOI":"10.1074\/mcp.M114.038984","article-title":"Quantitative proteomic analysis of host-virus interactions reveals a role for Golgi brefeldin A resistance factor 1 (GBF1) in dengue infection","volume":"13","author":"Carpp","year":"2014","journal-title":"Molecular & Cellular Proteomics"},{"key":"10.1111\/cmi.12804-BIB0006|cmi12804-cit-0007","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1053\/j.gastro.2015.09.011","article-title":"Sofosbuvir inhibits hepatitis E virus replication in vitro and results in an additive effect when combined with ribavirin","volume":"150","author":"Dao Thi","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1111\/cmi.12804-BIB0007|cmi12804-cit-0008","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jhep.2016.02.045","article-title":"Update on hepatitis E virology: Implications for clinical practice","volume":"65","author":"Debing","year":"2016","journal-title":"Journal of Hepatology"},{"key":"10.1111\/cmi.12804-BIB0008|cmi12804-cit-0009","doi-asserted-by":"crossref","first-page":"270","DOI":"10.3390\/v8100270","article-title":"Zoonotic hepatitis E virus: Classification, animal reservoirs and transmission routes","volume":"8","author":"Doceul","year":"2016","journal-title":"Virus"},{"key":"10.1111\/cmi.12804-BIB0009|cmi12804-cit-0010","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nrm1910","article-title":"ARF proteins: Roles in membrane traffic and beyond","volume":"7","author":"D'Souza-Schorey","year":"2006","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"10.1111\/cmi.12804-BIB0010|cmi12804-cit-0011","doi-asserted-by":"crossref","first-page":"e74491","DOI":"10.1371\/journal.pone.0074491","article-title":"Hepatitis C virus replication and Golgi function in brefeldin a-resistant hepatoma-derived cells","volume":"8","author":"Farhat","year":"2013","journal-title":"PLoS One"},{"key":"10.1111\/cmi.12804-BIB0011|cmi12804-cit-0012","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1111\/cmi.12572","article-title":"Identification of class II ADP-ribosylation factors as cellular factors required for hepatitis C virus replication","volume":"18","author":"Farhat","year":"2016","journal-title":"Cellular Microbiology"},{"key":"10.1111\/cmi.12804-BIB0012|cmi12804-cit-0013","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1146\/annurev.cellbio.23.090506.123209","article-title":"The small G proteins of the Arf family and their regulators","volume":"23","author":"Gillingham","year":"2007","journal-title":"Annual Review of Cell and Developmental Biology"},{"key":"10.1111\/cmi.12804-BIB0013|cmi12804-cit-0014","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1128\/JVI.01190-09","article-title":"Identification of GBF1 as a cellular factor required for hepatitis C virus RNA replication","volume":"84","author":"Goueslain","year":"2010","journal-title":"Journal of Virology"},{"key":"10.1111\/cmi.12804-BIB0014|cmi12804-cit-0015","doi-asserted-by":"crossref","first-page":"003","DOI":"10.1055\/s-0033-1338110","article-title":"Molecular virology of hepatitis E virus","volume":"33","author":"Holla","year":"2013","journal-title":"Seminars in Liver Disease"},{"key":"10.1111\/cmi.12804-BIB0015|cmi12804-cit-0016","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.cell.2010.03.050","article-title":"Viral reorganization of the secretory pathway generates distinct organelles for RNA replication","volume":"141","author":"Hsu","year":"2010","journal-title":"Cell"},{"key":"10.1111\/cmi.12804-BIB0016|cmi12804-cit-0017","doi-asserted-by":"crossref","first-page":"4103","DOI":"10.1242\/jcs.144899","article-title":"Arfs at a glance","volume":"127","author":"Jackson","year":"2014","journal-title":"Journal of Cell Science"},{"key":"10.1111\/cmi.12804-BIB0017|cmi12804-cit-0018","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0962-8924(99)01699-2","article-title":"Turning on ARF: The Sec7 family of guanine-nucleotide-exchange factors","volume":"10","author":"Jackson","year":"2000","journal-title":"Trends in Cell Biology"},{"key":"10.1111\/cmi.12804-BIB0018|cmi12804-cit-0019","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/liv.13037","article-title":"Extrahepatic manifestations of hepatitis E virus","volume":"36","author":"Kamar","year":"2016","journal-title":"Liver International"},{"key":"10.1111\/cmi.12804-BIB0019|cmi12804-cit-0020","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1083\/jcb.116.5.1071","article-title":"Brefeldin a: Insights into the control of membrane traffic and organelle structure","volume":"116","author":"Klausner","year":"1992","journal-title":"The Journal of Cell Biology"},{"key":"10.1111\/cmi.12804-BIB0020|cmi12804-cit-0021","doi-asserted-by":"crossref","first-page":"8259","DOI":"10.1073\/pnas.89.17.8259","article-title":"Computer-assisted assignment of functional domains in the nonstructural polyprotein of hepatitis E virus: Delineation of an additional group of positive-strand RNA plant and animal viruses","volume":"89","author":"Koonin","year":"1992","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1111\/cmi.12804-BIB0021|cmi12804-cit-0022","doi-asserted-by":"crossref","first-page":"11940","DOI":"10.1128\/JVI.01244-09","article-title":"GBF1, a guanine nucleotide exchange factor for Arf, is crucial for coxsackievirus B3 RNA replication","volume":"83","author":"Lanke","year":"2009","journal-title":"Journal of Virology"},{"key":"10.1111\/cmi.12804-BIB0022|cmi12804-cit-0023","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.jhep.2017.04.002","article-title":"Visualization of hepatitis E virus RNA and proteins in the human liver","volume":"67","author":"Lenggenhager","year":"2017","journal-title":"Journal of Hepatology"},{"key":"10.1111\/cmi.12804-BIB0023|cmi12804-cit-0024","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s12038-016-9659-0","article-title":"CSFV proliferation is associated with GBF1 and Rab2","volume":"42","author":"Liang","year":"2017","journal-title":"Journal of Biosciences"},{"key":"10.1111\/cmi.12804-BIB0024|cmi12804-cit-0025","doi-asserted-by":"crossref","first-page":"7535","DOI":"10.1128\/JVI.02684-09","article-title":"Differential effects of the putative GBF1 inhibitors Golgicide A and AG1478 on enterovirus replication","volume":"84","author":"Linden","year":"2010","journal-title":"Journal of Virology"},{"key":"10.1111\/cmi.12804-BIB0025|cmi12804-cit-0026","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2017.09.020","article-title":"Hepatitis E virus lifecycle and identification of 3 forms of the ORF2 capsid protein","author":"Montpellier","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1111\/cmi.12804-BIB0026|cmi12804-cit-0027","first-page":"3858","article-title":"Growth of human hepatoma cells lines with differentiated functions in chemically defined medium","volume":"42","author":"Nakabayashi","year":"1982","journal-title":"Cancer Research"},{"key":"10.1111\/cmi.12804-BIB0027|cmi12804-cit-0028","doi-asserted-by":"crossref","first-page":"e1002383","DOI":"10.1371\/journal.ppat.1002383","article-title":"SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication","volume":"7","author":"Neuvonen","year":"2011","journal-title":"PLoS Pathogens"},{"key":"10.1111\/cmi.12804-BIB0028|cmi12804-cit-0029","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1091\/mbc.E04-07-0599","article-title":"Dynamics of GBF1, a brefeldin A-sensitive Arf1 exchange factor at the Golgi","volume":"16","author":"Niu","year":"2005","journal-title":"Molecular Biology of the Cell"},{"key":"10.1111\/cmi.12804-BIB0029|cmi12804-cit-0030","doi-asserted-by":"crossref","first-page":"32","DOI":"10.5501\/wjv.v2.i2.32","article-title":"Architecture and biogenesis of plus-strand RNA virus replication factories","volume":"2","author":"Paul","year":"2013","journal-title":"WJV"},{"key":"10.1111\/cmi.12804-BIB0030|cmi12804-cit-0031","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1099\/vir.0.049577-0","article-title":"Early secretory pathway localization and lack of processing for hepatitis E virus replication protein pORF1","volume":"94","author":"Perttil\u00e4","year":"2013","journal-title":"Journal of General Virology"},{"key":"10.1111\/cmi.12804-BIB0031|cmi12804-cit-0032","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1128\/JVI.01854-08","article-title":"Deletions of the hypervariable region (HVR) in open reading frame 1 of hepatitis E virus do not abolish virus infectivity: Evidence for attenuation of HVR deletion mutants in vivo","volume":"83","author":"Pudupakam","year":"2009","journal-title":"Journal of Virology"},{"key":"10.1111\/cmi.12804-BIB0032|cmi12804-cit-0033","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.apsb.2014.06.006","article-title":"Curcumin inhibits the replication of enterovirus 71 in vitro","volume":"4","author":"Qin","year":"2014","journal-title":"Acta Pharmaceutica Sinica B"},{"key":"10.1111\/cmi.12804-BIB0033|cmi12804-cit-0034","doi-asserted-by":"crossref","first-page":"e1003056","DOI":"10.1371\/journal.ppat.1003056","article-title":"Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication","volume":"8","author":"Romero-Brey","year":"2012","journal-title":"PLoS Pathogens"},{"key":"10.1111\/cmi.12804-BIB0034|cmi12804-cit-0035","doi-asserted-by":"crossref","first-page":"2832","DOI":"10.1128\/JVI.80.6.2832-2841.2006","article-title":"Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus","volume":"80","author":"Rouille","year":"2006","journal-title":"Journal of Virology"},{"key":"10.1111\/cmi.12804-BIB0035|cmi12804-cit-0036","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/nchembio.144","article-title":"Golgicide a reveals essential roles for GBF1 in Golgi assembly and function","volume":"5","author":"S\u00e1enz","year":"2009","journal-title":"Nature Chemical Biology"},{"key":"10.1111\/cmi.12804-BIB0036|cmi12804-cit-0037","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1002\/hep.27990","article-title":"Is hepatitis E virus an emerging problem in industrialized countries?","volume":"62","author":"Sayed","year":"2015","journal-title":"Hepatology"},{"key":"10.1111\/cmi.12804-BIB0037|cmi12804-cit-0038","doi-asserted-by":"crossref","first-page":"5697","DOI":"10.1128\/JVI.00146-12","article-title":"Adaptation of a genotype 3 hepatitis E virus to efficient growth in cell culture depends on an inserted human gene segment acquired by recombination","volume":"86","author":"Shukla","year":"2012","journal-title":"Journal of Virology"},{"key":"10.1111\/cmi.12804-BIB0038|cmi12804-cit-0039","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1099\/vir.0.068429-0","article-title":"Consensus proposals for classification of the family Hepeviridae","volume":"95","author":"Smith","year":"2014","journal-title":"Journal of General Virology"},{"key":"10.1111\/cmi.12804-BIB0039|cmi12804-cit-0040","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/0042-6822(91)90760-9","article-title":"Hepatitis E virus (HEV): Molecular cloning and sequencing of the full-length viral genome","volume":"185","author":"Tam","year":"1991","journal-title":"Virology"},{"key":"10.1111\/cmi.12804-BIB0040|cmi12804-cit-0041","doi-asserted-by":"crossref","first-page":"5888","DOI":"10.1074\/jbc.M611145200","article-title":"Reticulon 3 binds the 2C protein of enterovirus 71 and is required for viral replication","volume":"282","author":"Tang","year":"2007","journal-title":"Journal of Biological Chemistry"},{"key":"10.1111\/cmi.12804-BIB0041|cmi12804-cit-0042","doi-asserted-by":"crossref","first-page":"e1000088","DOI":"10.1371\/journal.ppat.1000088","article-title":"Mouse hepatitis coronavirus RNA replication depends on GBF1-mediated ARF1 activation","volume":"4","author":"Verheije","year":"2008","journal-title":"PLoS Pathogens"},{"key":"10.1111\/cmi.12804-BIB0042|cmi12804-cit-0043","doi-asserted-by":"crossref","first-page":"4372","DOI":"10.1128\/JVI.00055-15","article-title":"Cell-specific establishment of poliovirus resistance to an inhibitor targeting a cellular protein","volume":"89","author":"Viktorova","year":"2015","journal-title":"Journal of Virology"},{"key":"10.1111\/cmi.12804-BIB0043|cmi12804-cit-0044","doi-asserted-by":"crossref","first-page":"e99768","DOI":"10.1371\/journal.pone.0099768","article-title":"Class I ADP-ribosylation factors are involved in enterovirus 71 replication","volume":"9","author":"Wang","year":"2014","journal-title":"PLoS One"},{"key":"10.1111\/cmi.12804-BIB0044|cmi12804-cit-0045","doi-asserted-by":"crossref","first-page":"5238","DOI":"10.1128\/JVI.02680-06","article-title":"Molecular determinants of the interaction between coxsackievirus protein 3A and guanine nucleotide exchange factor GBF1","volume":"81","author":"Wessels","year":"2007","journal-title":"Journal of Virology"},{"key":"10.1111\/cmi.12804-BIB0045|cmi12804-cit-0046","doi-asserted-by":"crossref","first-page":"11852","DOI":"10.1128\/JVI.01225-06","article-title":"Effects of picornavirus 3A proteins on protein transport and GBF1-dependent COP-I recruitment","volume":"80","author":"Wessels","year":"2006","journal-title":"Journal of Virology"}],"container-title":["Cellular Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcmi.12804","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/cmi.12804\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T06:01:46Z","timestamp":1643349706000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cmi.12804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,17]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"URL":"https:\/\/doi.org\/10.1111\/cmi.12804","archive":["Portico"],"relation":{},"ISSN":["1462-5814"],"issn-type":[{"value":"1462-5814","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11,17]]}}}