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Nevertheless, controversies exist for indications of <jats:styled-content style=\"fixed-case\">DAPT<\/jats:styled-content>. In view of evidence\u2010based medicine analysis, patients with high\u2010risk transient ischemic attack and minor stroke, severe symptomatic intracranial artery stenosis, symptomatic intracranial and extracranial artery stenosis causing artery\u2010to\u2010artery embolism, ischemic stroke attributed to aortic arch plaques, high\u2010risk atrial fibrillation not suitable for oral anticoagulants, intracranial and extracranial stent implantation, and ischemic stroke with acute coronary syndrome may gain great benefit from <jats:styled-content style=\"fixed-case\">DAPT<\/jats:styled-content> of clopidogrel and aspirin. 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