{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T18:55:41Z","timestamp":1792263341313,"version":"4.4.0"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T00:00:00Z","timestamp":1611014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005089","name":"Beijing Municipal Natural Science Foundation","doi-asserted-by":"publisher","award":["7202021"],"award-info":[{"award-number":["7202021"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["CNS Neurosci Ther"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>We analyzed the resting state functional magnetic resonance images to investigate the alterations of neural networks in patients with glioma\u2010related epilepsy (GRE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010six patients with right temporal lower\u2010grade glioma were divided into GRE (<jats:italic>n<\/jats:italic>\u00a0=\u00a028) and non\u2010GRE groups. Twenty\u2010eight healthy subjects were recruited after matching age, sex, and education level. Sensorimotor, visual, language, and left executive control networks were applied to generate functional connectivity matrices, and their topological properties were investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant alterations in functional connectivity were found. The least significant discovery test revealed differences only in the language network. The shortest path length, clustering coefficient, local efficiency, and vulnerability were greater in the non\u2010GRE group than in the other groups. The nodal efficiencies of two nodes (mirror areas to Broca and Wernicke) were weaker in the non\u2010GRE group than in the other groups. The node of degree centrality (Broca), nodal local efficiency (Wernicke), and nodal clustering coefficient (temporal polar) were greater in the non\u2010GRE group than in the healthy group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Different tumor locations alter different neural networks. Temporal lobe gliomas in the right hemisphere altered the language network. Glioma itself and GRE altered the network in opposing ways in patients with right temporal glioma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cns.13595","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T16:40:08Z","timestamp":1611074408000},"page":"363-371","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Epilepsy enhance global efficiency of language networks in right temporal lobe gliomas"],"prefix":"10.1111","volume":"27","author":[{"given":"Shengyu","family":"Fang","sequence":"first","affiliation":[{"name":"Beijing Neurosurgical Institute, Capital Medical University Beijing China"},{"name":"Department of Neurosurgery Beijing Tiantan Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinyan","family":"Wang","sequence":"additional","affiliation":[{"name":"Beijing Neurosurgical Institute, Capital Medical University Beijing China"},{"name":"Department of Neurosurgery Beijing Tiantan Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7008-6351","authenticated-orcid":false,"given":"Tao","family":"Jiang","sequence":"additional","affiliation":[{"name":"Beijing Neurosurgical Institute, Capital Medical University Beijing China"},{"name":"Department of Neurosurgery Beijing Tiantan Hospital Capital Medical University Beijing China"},{"name":"Research Unit of Accurate Diagnosis, Treatment, and Translational Medicine of Brain Tumors Chinese Academy of Medical Sciences Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2362"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2018.01.011"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/nox130"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2016160422"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2017.00038"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhq291"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005226"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv130"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005733"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.00684"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-016-1545-1"},{"key":"e_1_2_11_13_1","first-page":"458","article-title":"Corrigendum: GRETNA: a graph theoretical network analysis toolbox for imaging connectomics","volume":"9","author":"Wang J","year":"2015","journal-title":"Front Hum Neurosci"},{"key":"e_1_2_11_14_1","first-page":"386","article-title":"GRETNA: a graph theoretical network analysis toolbox for imaging connectomics","volume":"9","author":"Wang J","year":"2015","journal-title":"Front Hum Neurosci"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhw157"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-017-9693-z"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2014.11.018"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22877"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.3171\/2019.6.FOCUS19346"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.12.JNS14629"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pjnns.2017.07.010"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.4103\/sni.sni_414_17"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2016.05.002"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000004176"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2018.10.034"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2006.12.002"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00950.2006"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.71.015103"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-020-04322-8"}],"container-title":["CNS Neuroscience &amp; 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