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Further group comparisons of <jats:sup>18<\/jats:sup>F\u2010FDG\u2010PET data were carried out between prognostic subgroups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:sup>18<\/jats:sup>F\u2010FDG\u2010PET was abnormal in 81% patients with anti\u2010GABAB receptor encephalitis and was more sensitive than MRI (81% vs. 42.9%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.025). Alter limbic lobe glucose metabolism (mostly hypermetabolism) was observed in 14 patients (66.7%), of whom 10 (10\/14, 71.4%) demonstrated hypermetabolism in the medial temporal lobe (MTL). Group analysis also confirmed MTL hypermetabolism in association with relative frontal and parietal hypometabolism was a general metabolic pattern. After a median follow\u2010up of 33\u00a0months, the group comparisons revealed that patients with poor outcome demonstrated increased metabolism in the MTL compared to those with good outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:sup>18<\/jats:sup>F\u2010FDG\u2010PET may be more sensitive than MRI in the early diagnosis of anti\u2010GABAB receptor encephalitis. MTL hypermetabolism was associated with relative frontal or parietal hypometabolism and may serve as a prognostic biomarker in anti\u2010GABAB receptor encephalitis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cns.13767","type":"journal-article","created":{"date-parts":[[2021,11,27]],"date-time":"2021-11-27T07:52:56Z","timestamp":1637999576000},"page":"269-278","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["<sup>18<\/sup>F\u2010fluorodeoxy\u2010glucose positron emission tomography pattern and prognostic predictors in patients with anti\u2010GABAB receptor encephalitis"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4221-5061","authenticated-orcid":false,"given":"Xiao","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Neurology Beijing Tiantan Hospital Capital Medical University  Beijing China"},{"name":"China National Clinical Research Center for Neurological 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