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Demographic information, nutritional status, and gait performance were compared between the two groups, and the correlation between nutritional status and gait performance was subsequently analyzed by Pearson and Spearman correlation analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The AD\u2010D group had lower scores on Mini\u2010Nutritional Assessment (MNA) and MNA\n                      <jats:sup>m<\/jats:sup>\n                      scales, lower levels of urea nitrogen, folic acid, and vitamin B\n                      <jats:sub>12<\/jats:sub>\n                      in blood, and higher homocysteine level than those in the AD\u2010MCI group (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). The AD\u2010D group had slower step speed, shorter step length, and shorter stride length than those in the AD\u2010MCI group (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). AD patients with decreased scores of MNA and MNA\n                      <jats:sup>m<\/jats:sup>\n                      scales, and declined levels of urea nitrogen and vitamin B\n                      <jats:sub>12<\/jats:sub>\n                      in blood had reduced gait speed and gait cadence, and prolonged step length time and stride length time, whereas homocysteine showed the almost opposite results (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). In the AD\u2010MCI group, the score of scale was negatively correlated with the coefficient of variation (CV) of stride length, and the folic acid level was negatively correlated with the CV of stride length and cadence (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>AD patients at the dementia stage had worse nutritional status and gait performance than those at the MCI stage, which was associated with worse global cognition and activities of daily living. Poorer nutritional status was associated with higher gait variability in patients at the MCI stage and with poorer gait performance in patients at the dementia stage. Early identification and intervention of patients with nutritional risk or malnutrition may improve gait performance, thus reducing the risk of falling and cognitive decline, as well as the mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cns.14502","type":"journal-article","created":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T23:54:55Z","timestamp":1699660495000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Association between nutritional status and gait performance in Alzheimer's disease"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8825-3771","authenticated-orcid":false,"given":"Mingyue","family":"He","sequence":"first","affiliation":[{"name":"Department of Neurology, Beijing Tiantan Hospital Capital Medical University  Beijing 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