{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:29:03Z","timestamp":1792092543122,"version":"4.4.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T00:00:00Z","timestamp":1699747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["CNS Neurosci Ther"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To explore the relationship between asymmetric deep cerebral venous (ADCV) filling and poor outcomes after endovascular treatment (EVT) in patients with acute basilar artery occlusion (ABAO).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>ABAO patients were selected from a prospectively collected data at our center. The DCV filling was evaluated using computed tomography perfusion (CTP)\u2010derived reconstructed 4D\u2010DSA or mean venous map. ADCV filling was defined as the internal cerebral vein (ICV), thalamostriate vein (TSV), or basal vein of Rosenthal (BVR) presence of ipsilateral filling defects or delayed opacification compared to the contralateral side. Poor prognosis was defined as a modified Rankin scale score &gt;3 at the 90\u2010day follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 90 patients were enrolled in the study, with a median Glasgow Coma Scale of 6, 46 (51.1%) showed ADCV filling, 59 (65.6%) had a poor prognosis, and 27 (30.7%) had malignant cerebellar edema (MCE). Multivariate adjusted analysis revealed significant associations between asymmetric TSV and poor prognosis (odds ratio, 9.091, <jats:italic>p<\/jats:italic>\u2009=\u20090.006); asymmetric BVR (OR, 9.232, <jats:italic>p<\/jats:italic>\u2009=\u20090.001) and asymmetric ICV (OR, 4.028, <jats:italic>p<\/jats:italic>\u2009=\u20090.041) were significantly associated with MCE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Preoperative ADCV filling is an independent influencing factor for the poor outcome after EVT in ABAO patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cns.14513","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T05:27:45Z","timestamp":1699853265000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Asymmetric deep cerebral venous filling predicts poor outcome of acute basilar artery occlusion after endovascular treatment"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4611-9138","authenticated-orcid":false,"given":"Huiyuan","family":"Wang","sequence":"first","affiliation":[{"name":"Center for Rehabilitation Medicine, Department of Neurology Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College)  Hangzhou China"},{"name":"School of Clinical Medicine, Graduate School Bengbu Medical College  Bengbu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panpan","family":"Shen","sequence":"additional","affiliation":[{"name":"Center for Rehabilitation Medicine, Department of Neurology Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College)  Hangzhou China"},{"name":"The Second Clinical Medical College Zhejiang Traditional Chinese Medicine University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Yu","sequence":"additional","affiliation":[{"name":"Alberta Institute Wenzhou Medical University  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yafei","family":"Shang","sequence":"additional","affiliation":[{"name":"Center for Rehabilitation Medicine, Department of Neurology Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College)  Hangzhou China"},{"name":"School of Clinical Medicine, Graduate School Bengbu Medical College  Bengbu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Xu","sequence":"additional","affiliation":[{"name":"Center for Rehabilitation Medicine, Department of Neurology Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College)  Hangzhou China"},{"name":"The Second Clinical Medical College Zhejiang Traditional Chinese Medicine University 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