{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T10:54:57Z","timestamp":1791802497337,"version":"4.3.4"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T00:00:00Z","timestamp":1710201600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["CNS Neurosci Ther"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>With the progress of thrombectomy technology, the vascular recanalization rate of patients with stroke has been continuously improved, but the proportion of futile recanalization (FR) is still quite a few. The long\u2010term prognosis and survival of patients with FR and its influencing factors remain unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients who received endovascular treatment (EVT) for ischemic stroke were enrolled between 2013 and 2021 from a single\u2010center prospectively registry study. We evaluated the long\u2010term outcome of these patients by Kaplan\u2013Meier survival analysis, and the multivariable logistic regression curve was performed to analyze influencing factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 458 patients with FR, 56.4% of patients survived at 1\u2009year, and 50.4% at 2\u2009years. In the multivariate regression analysis, age, premorbid modified Rankin Scale (mRS), National Institutes of Health Stroke Scale (NIHSS), posterior circulation infarct, general anesthesia, symptomatic intracerebral hemorrhage (sICH), and decompressive craniectomy were found to be related to unfavorable outcomes in long\u2010term. Age, premorbid mRS, NIHSS, general anesthesia, and sICH were predictors of long\u2010term mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Futile recanalization accounts for a large proportion of stroke patients after thrombectomy. This study on the long\u2010term prognosis of such patients is beneficial to the formulation of treatment plans and the prediction of therapeutic effects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cns.14588","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T05:39:27Z","timestamp":1710308367000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Long term for patients with futile endovascular reperfusion after stroke"],"prefix":"10.1111","volume":"30","author":[{"given":"Mengke","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Neurology, Xuanwu Hospital Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0736-7900","authenticated-orcid":false,"given":"Ruiwen","family":"Che","sequence":"additional","affiliation":[{"name":"Department of Neurology, Beijing ShiJiTan Hospital 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of smoking on one year functional outcomes after thrombectomy for young stroke patients","volume":"15","author":"Peng SH","year":"2022","journal-title":"J Neurointerv Surg"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000517929"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2022.106832"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3233\/NRE-220269"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2020.06.209"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.11455"}],"container-title":["CNS Neuroscience &amp; 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