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The maturation of brain network is crucial during adolescence, yet the abnormal alternations in depressed adolescents with NSSI or NSSI+SA remain poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Resting\u2010state functional magnetic resonance imaging data were collected from 114 depressed adolescents, classified into three groups: clinical control (non\u2010self\u2010harm), NSSI only, and NSSI+SA based on self\u2010harm history. The alternations of resting\u2010state functional connectivity (RSFC) were identified through support vector machine\u2010based classification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Convergent alterations in NSSI and NSSI+SA predominantly centered on the inter\u2010network RSFC between the Limbic network and the three core neurocognitive networks (SalVAttn, Control, and Default networks). Divergent alterations in the NSSI+SA group primarily focused on the Visual, Limbic, and Subcortical networks. Additionally, the severity of depressive symptoms only showed a significant correlation with altered RSFCs between Limbic and DorsAttn or Visual networks, strengthening the fact that increased depression severity alone does not fully explain observed FC alternations in the NSSI+SA group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Convergent alterations suggest a shared neurobiological mechanism along the self\u2010destructiveness continuum. Divergent alterations may indicate biomarkers differentiating risk for SA, informing neurobiologically guided interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cns.14684","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T10:53:47Z","timestamp":1715597627000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Unveiling convergent and divergent intrinsic brain network alternations in depressed adolescents engaged in non\u2010suicidal self\u2010injurious behaviors with and without suicide attempts"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7767-7202","authenticated-orcid":false,"given":"Linling","family":"Li","sequence":"first","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, International Health Science Innovation Center, 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