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The execution of CF\u2010related tasks depends on the collective interaction of various neural circuits in essential brain regions, such as the prefrontal, anterior cingulate, and posterior parietal cortices, which support the harmonic and smooth transition of thoughts and perspectives. Therefore, clarifying the mechanism of CF and introducing non\u2010invasive neuromodulatory methods that enhance CF provides a way for developing new treatment approaches.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This review systematically investigates the application of photobiomodulation (PBM), neurofeedback (NF), repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), and virtual reality (VR) as non\u2010invasive neuromodulatory techniques for modulating cognitive behaviors related to CF in neuropsychological conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Considering the vital role of CF in executive functions, deficits in CF impair adaptive behavior in neuropsychological conditions such as schizophrenia, autism spectrum disorder (ASD), and age\u2010related cognitive decline. Some technology\u2010based interventions, including PBM, NF, rTMS, tDCS, and VR, have been developed to non\u2010invasively modulate the switching capability and strategies of the mind. These non\u2010invasive interventions provide targeted neuromodulation on neural circuits and have demonstrated a promising effect in improving cognitive processes, including CF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The present study provides a comprehensive review of the therapeutic consequences of non\u2010invasive neuromodulatory methods on CF in neurological conditions. This insight can offer a perspective for planning various research strategies and clinical approaches aimed at improving CF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cns.70613","type":"journal-article","created":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T10:41:11Z","timestamp":1758019271000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["How to Improve Cognitive Flexibility: Evidence From Noninvasive Neuromodulation Techniques"],"prefix":"10.1111","volume":"31","author":[{"given":"Naeimeh Akbari","family":"Gharalari","sequence":"first","affiliation":[{"name":"Neurophysiology Research Center, Cellular and Molecular Medicine Research Institute Urmia University of Medical Sciences  Urmia 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