{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T18:32:08Z","timestamp":1761762728499,"version":"build-2065373602"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2503804"],"award-info":[{"award-number":["2022YFC2503804"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071461","82271503","82571656"],"award-info":[{"award-number":["82071461","82271503","82571656"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of Hunan Province","doi-asserted-by":"publisher","award":["2024JJ6695"],"award-info":[{"award-number":["2024JJ6695"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["CNS Neurosci Ther"],"published-print":{"date-parts":[[2025,10]]},"abstract":"ABSTRACT<\/jats:title>\n \n Aim<\/jats:title>\n To explore the emotion recognition (ER) abilities among temporal lobe epilepsy (TLE) patients with different levels of depression.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This observational study was conducted during December 2021 and November 2022, including 71 healthy controls (HCs) and 93 TLE patients. Based on the scores of the Beck Depression Index, the patients were divided into four groups (no\/mild\/moderate\/severe depression). All participants finished the Faux pas task (FPT), watched the dynamic facial expression task and recognized the emotion (anger, disgust, happiness, or sadness) with the recording of eye movements. The accuracy of ER was recorded. The percentage of fixation in interested areas (IA) and fixation counts in IA were selected and analyzed.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n TLE patients without depression had significantly lower FPT scores (\n p<\/jats:italic>\n \u2009=\u20090.001) and accuracy ratios of dynamic facial ER (\n p<\/jats:italic>\n \u2009=\u20090.039) than HCs. Patients with severe depression had significantly more fixation percentages and fixation counts in the nose than patients with no\/mild\/moderate depression (\n p<\/jats:italic>\n \u2009<\u20090.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The recording of eye movement provides more accurate and objective biobehavioral indicators for distinguishing TLE patients with severe depression, which has great practical significance for early monitoring and intervention.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/cns.70636","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T18:21:37Z","timestamp":1761762097000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["More Fixations in Static Facial Regions During Emotion Recognition Among\n TLE<\/scp>\n Patients With Severe Depression"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4410-3234","authenticated-orcid":false,"given":"Haojun","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Xiangya Hospital of Central South University Changsha China"},{"name":"National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiong","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University Changsha China"},{"name":"Department of Neurology Xiangya Hospital of Central South University Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7666-9558","authenticated-orcid":false,"given":"Kailing","family":"Huang","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University Changsha China"},{"name":"Department of Neurology Xiangya Hospital of Central South University Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7658-1399","authenticated-orcid":false,"given":"Li","family":"Feng","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University Changsha China"},{"name":"Department of Neurology Xiangya Hospital of Central South University Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.yebeh.2016.04.024","article-title":"Social Cognition in Temporal Lobe Epilepsy: A Systematic Review and Meta\u2010Analysis","volume":"60","author":"Bora E.","year":"2016","journal-title":"Epilepsy & Behavior"},{"issue":"46","key":"e_1_2_12_3_1","doi-asserted-by":"crossref","first-page":"8782","DOI":"10.1523\/JNEUROSCI.1280-20.2020","article-title":"Linking Social Cognition to Learning and Memory","volume":"40","author":"Leblanc H.","year":"2020","journal-title":"Journal of Neuroscience"},{"issue":"10","key":"e_1_2_12_4_1","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/nrn4005","article-title":"Social Cognition in Schizophrenia","volume":"16","author":"Green M. 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