{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:41:27Z","timestamp":1772160087045,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,11,19]],"date-time":"2012-11-19T00:00:00Z","timestamp":1353283200000},"content-version":"vor","delay-in-days":49,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:p>\n                    <jats:italic>Clin. Otolaryngol.<\/jats:italic>\n                    2012,\n                    <jats:bold>37<\/jats:bold>\n                    , 355\u2013361\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Objectives:\u2002<\/jats:bold>\n                    To evaluate the vascularisation process of the grafted fascia or perichondrium in active and inactive chronic mucosal otitis media.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design:\u2002<\/jats:bold>\n                    Prospective study.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Setting:\u2002<\/jats:bold>\n                    University\u2010based, secondary referral hospital.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Participants:\u2002<\/jats:bold>\n                    Two hundred thirty\u2010two patients who underwent type 1 tympanoplasty or myringoplasty by one experienced surgeon.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Main outcome measures:\u2002<\/jats:bold>\n                    After postoperative days 5\u20137, the graft was inspected using a binocular operating microscope at least twice weekly until vascularisation was confirmed to have commenced. This point was defined as the time of vascularisation. An intact graft at 3\u2003months postoperatively was considered a closure success.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:\u2002<\/jats:bold>\n                    The mean time of vascularisation of 232 grafts was 14.2\u2003\u00b1\u20033.6\u2003days (range 8\u201325). The vascularisation time differed according to the perforation size. The perforations involving 50% and less of the pars tensa were revascularised earlier than those involving 75% and more. There was no relationship between vascularisation time and closure success or failure. Age itself did not influence the vascularisation time or the risk of closure failure. Postoperative otorrhea was higher in patients with a preoperative wet middle ear mucosa than among those with a dry one.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:\u2002<\/jats:bold>\n                    The vascularisation time was shorter in perforations of 50% and less than those of 75% and more but the rate of closure success was not different between two. The graft failure was not attributed to the failure of vascularisation. Age itself seemed not to be a contraindication for myringo\u2010\/tympanoplasty in otherwise healthy elderly patients.\n                  <\/jats:p>","DOI":"10.1111\/coa.12014","type":"journal-article","created":{"date-parts":[[2012,9,5]],"date-time":"2012-09-05T11:52:13Z","timestamp":1346845933000},"page":"355-361","source":"Crossref","is-referenced-by-count":14,"title":["Vascularisation of myringo\u2010\/tympanoplastic grafts in active and inactive chronic mucosal otitis media: a prospective cohort study"],"prefix":"10.1111","volume":"37","author":[{"given":"H.","family":"Noh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.\u2010H.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,11,19]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100120274"},{"key":"e_1_2_9_3_2","first-page":"2342","volume-title":"Fitzpatrick\u2019s Dermatology in General Medicine","author":"Falanga V.","year":"2008"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000201459.91559.7f"},{"key":"e_1_2_9_5_2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/BF00454257","article-title":"Revascularization of fascia after tympanoplastic grafts. A study by fluorescein angiography","volume":"239","author":"Pau H.W.","year":"1984","journal-title":"Arch Otorhinolaryngol"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348948609500501"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197902000-00009"},{"key":"e_1_2_9_8_2","first-page":"CD003996","article-title":"Antibiotic prophylaxis in clean and clean\u2010contaminated ear surgery","volume":"1","author":"Verschuur H.P.","year":"2004","journal-title":"Cochrane Database Syst. Rev."},{"key":"e_1_2_9_9_2","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1177\/0194599811404963","article-title":"Graft uptake rates with isoamyl\u20102\u2010cyanoacrylate in myringoplasty procedures: a 10\u2010year retrospective study","volume":"145","author":"Deenadayal D.S.","year":"2011","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"e_1_2_9_10_2","first-page":"126","article-title":"Effect of the use of dry (rigid) or wet (soft) temporal fascia graft on tympanoplasty","volume":"38","author":"Alkan S.","year":"2009","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"e_1_2_9_11_2","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s15010-010-0048-6","article-title":"A pre\u2010 and postoperative bacteriological study of chronic suppurative otitis media","volume":"38","author":"Shim H.J.","year":"2010","journal-title":"Infection"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-010-1405-x"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31818cbeb1"}],"container-title":["Clinical Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcoa.12014","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.12014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T13:03:26Z","timestamp":1698757406000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/coa.12014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1111\/coa.12014"],"URL":"https:\/\/doi.org\/10.1111\/coa.12014","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717989063.793472516","asserted-by":"object"}]},"ISSN":["1749-4478","1749-4486"],"issn-type":[{"value":"1749-4478","type":"print"},{"value":"1749-4486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}