{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:26:17Z","timestamp":1782253577836,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,6,10]],"date-time":"2013-06-10T00:00:00Z","timestamp":1370822400000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Patients with peripheral facial palsy frequently complain of fluid leakage and food retention during meals. We investigated oral function during eating in adults with peripheral facial palsy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A prospective two\u2010phase controlled observational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Data were collected at the <jats:styled-content style=\"fixed-case\">ENT<\/jats:styled-content> clinic in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ihon <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>niversity <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>tabashi <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital (patients) and <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ihon <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>niversity <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ental <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital (controls) between <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eptember 2009 and <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ugust 2011 and analysed at the <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>epartment of <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ral <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>iagnostic <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ciences in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ihon <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>niversity <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>chool of <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>entistry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Fourteen patients with acute idiopathic facial palsy and 14 controls completed <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tudy 1. Sixteen patients with acute idiopathic facial palsy and 16 controls completed <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tudy 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>In <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tudy 1, oral vestibular cleansing capability was assessed by measuring the amount of rice remaining in the oral vestibule after mastication. In <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tudy 2, masticatory efficiency was evaluated by measuring glucose eluted from gummy jelly during chewing. These oral functions were observed at the first visit and final visit (after patients with facial palsy had recovered).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Oral vestibular cleansing capability at the first visit was significantly decreased by facial palsy (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001 <jats:italic>versus<\/jats:italic> healthy volunteers and <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001 <jats:italic>versus<\/jats:italic> contralateral side) but recovered as facial muscular function improved (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.034). There was a significant correlation between improvement in paralysis and decreased food retention (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u22120.528, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.010). At the first visit, masticatory efficiency on the affected side was significantly lower than that of controls (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.002) but had mostly recovered after resolution of facial palsy (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.033).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Oral functions were decreased by peripheral facial palsy. Oral vestibular cleansing capability was more significantly associated than masticatory efficiency with facial muscle function. Our data suggest that peripheral facial palsy impairs eating and worsens oral hygiene, which may result in oral disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.12118","type":"journal-article","created":{"date-parts":[[2013,4,23]],"date-time":"2013-04-23T09:30:25Z","timestamp":1366709425000},"page":"231-236","source":"Crossref","is-referenced-by-count":7,"title":["Quantitative evaluation of oral function in acute and recovery phase of idiopathic facial palsy; a preliminary controlled study"],"prefix":"10.1111","volume":"38","author":[{"given":"Y.","family":"Kato","sequence":"first","affiliation":[{"name":"Department of Oral Diagnostic Sciences Nihon University School of Dentistry Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Kamo","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostic Sciences Nihon University School of Dentistry Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostic Sciences Nihon University School of Dentistry Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostic Sciences Nihon University School of Dentistry Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Okada\u2010Ogawa","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostic Sciences Nihon University School of Dentistry Tokyo Japan"},{"name":"Division of Clinical Research Dental Research Center Nihon University School of Dentistry Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Noma","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostic Sciences Nihon University School of Dentistry Tokyo Japan"},{"name":"Division of Clinical Research Dental Research Center Nihon University School of Dentistry Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Kukimoto","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Nihon University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Omori","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Nihon University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Nakazato","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Nihon University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Kishi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Nihon University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Nihon University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Imamura","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostic Sciences Nihon University School of Dentistry Tokyo Japan"},{"name":"Division of Clinical Research Dental Research Center Nihon University School of Dentistry Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2007.01747.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-006-9062-3"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2010.06.004"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.1979.tb00399.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181ab3362"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1996.0173"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.77.1.142"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-4-431-53942-1_16"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200411000-00027"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200303000-00033"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(99)00049-8"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2010.02112.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpor.2009.04.001"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.2186\/prp.5.104"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2010.02197.x"},{"key":"e_1_2_9_17_1","first-page":"168","article-title":"Effect of salivary flow rate on masticatory efficiency","volume":"22","author":"Gomes S.G.","year":"2009","journal-title":"Int. J. Prosthodont."},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.2186\/jjps.51.563"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1994.tb01260.x"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2010.02105.x"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034510383860"},{"key":"e_1_2_9_22_1","first-page":"19","volume-title":"The Facial Nerve","author":"Many M.","year":"2000"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000157694.57872.82"}],"container-title":["Clinical Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcoa.12118","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.12118","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T10:48:10Z","timestamp":1700650090000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/coa.12118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["10.1111\/coa.12118"],"URL":"https:\/\/doi.org\/10.1111\/coa.12118","archive":["Portico"],"relation":{},"ISSN":["1749-4478","1749-4486"],"issn-type":[{"value":"1749-4478","type":"print"},{"value":"1749-4486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}