{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T19:39:26Z","timestamp":1789241966269,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,12,17]],"date-time":"2013-12-17T00:00:00Z","timestamp":1387238400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>osition <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>aper on <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>hinosinusitis and <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>asal <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>olyps describes methods to perform population\u2010based and clinical studies on chronic rhinosinusitis in a standardised way, and it also describes how to clinical investigate <jats:styled-content style=\"fixed-case\">CRS<\/jats:styled-content>. The aim of this cross\u2010sectional study was to evaluate quality of life and objective findings in persons with chronic rhinosinusitis recruited from the general population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>As part of a trans\u2010<jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean study, selected respondents to a survey questionnaire were invited for a clinical visit. Subjective symptoms and rhinoscopy were used for the clinical diagnosis of chronic rhinosinusitis, and persons with and without chronic rhinosinusitis were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>This research took place in the department of Otolaryngology, Odense University Hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>A total of 366 persons participated at the clinical visit, and of these, 91 were diagnosed with chronic rhinosinusitis, 271 without chronic rhinosinusitis and four persons were excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Severity of symptoms and disease\u2010specific quality of life were measured using the <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ino\u2010<jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>asal <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>utcome <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>est 22, and generic quality of life was measured using <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean quality of life \u2013 5 dimensions including an index score and a visual analogue scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of chronic rhinosinusitis was 9%, and the prevalence of polyps was 4%. Persons with chronic rhinosinusitis had significantly reduced disease\u2010specific quality of life (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.00) and generic quality of life (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.04 and 0.01) compared with persons without chronic rhinosinusitis. Having chronic rhinosinusitis was correlated to age, allergic rhinitis and smell.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study gives insight into health\u2010related quality of life and objective findings in persons with chronic rhinosinusitis recruited from the general population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.12189","type":"journal-article","created":{"date-parts":[[2013,10,16]],"date-time":"2013-10-16T16:18:42Z","timestamp":1381940322000},"page":"474-480","source":"Crossref","is-referenced-by-count":78,"title":["Quality of life and associated factors in persons with chronic rhinosinusitis in the general population: A prospective questionnaire and clinical cross\u2010sectional study"],"prefix":"10.1111","volume":"38","author":[{"given":"B.","family":"Lange","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Odense University Hospital University of Southern Denmark Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Holst","sequence":"additional","affiliation":[{"name":"Department of Biostatistics University of Southern Denmark Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Thilsing","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine Odense University Hospital Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Baelum","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine Odense University Hospital Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Kjeldsen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Odense University Hospital University of Southern Denmark Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-010-0175-2"},{"key":"e_1_2_11_3_1","first-page":"1","article-title":"European position paper on rhinosinusitis and nasal polyps 2007","volume":"20","author":"Fokkens W.","year":"2007","journal-title":"Rhinol. 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