{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:06:25Z","timestamp":1791806785652,"version":"4.3.4"},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,7,16]],"date-time":"2014-07-16T00:00:00Z","timestamp":1405468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to assess self\u2010report and perceptual voice outcomes in patients undergoing local anaesthetic injection laryngoplasty in our outpatient clinic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Department of Otolaryngology\u2010Head and Neck Surgery, Freeman Hospital, Newcastle\u2010upon\u2010Tyne, <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Sixty\u2010eight patients underwent local anaesthetic injection laryngoplasty in the outpatient clinic over the 2\u2010year study period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measure<\/jats:title><jats:p>Voice Performance Questionnaire (patient\u2010rated), and perceptual voice analysis (observer\u2010rated) Grade, Roughness, Breathiness, Aesthenia and Strain scores were recorded before and 2\u00a0weeks after injection laryngoplasty.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010seven patients had sufficient pre\u2010 and post\u2010procedure data to be included in the analysis. These included 32 men and 25 women, age range 26\u201397\u00a0years. Of the remaining patients, they were excluded due to failed procedure (<jats:italic>n<\/jats:italic>\u00a0=\u00a03), too unwell to proceed (<jats:italic>n<\/jats:italic>\u00a0=\u00a01), died before follow\u2010up was complete (<jats:italic>n<\/jats:italic>\u00a0=\u00a03) and incomplete data (<jats:italic>n<\/jats:italic>\u00a0=\u00a04). The median Voice Performance Questionnaire score improved from 42 to 21; (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001). Significant improvements were seen in all parameters of Grade, Roughness, Breathiness, Aesthenia, Strain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Injection laryngoplasty under local anaesthetic in the outpatient clinic generates improvements in subjective and perceptual voice outcomes similar to those obtained in the operating room under general anaesthetic or sedation. Complication rates between these procedures were also comparable. Injection laryngoplasty under local anaesthetic is timely, cost\u2010effective and obviates need for general anaesthesia in patients, many of whom have comorbidities and diminished life expectancy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.12274","type":"journal-article","created":{"date-parts":[[2014,6,13]],"date-time":"2014-06-13T16:21:05Z","timestamp":1402676465000},"page":"224-227","source":"Crossref","is-referenced-by-count":23,"title":["Injection laryngoplasty in the outpatient clinic under local anaesthetic: a case series of sixty\u2010eight patients"],"prefix":"10.1111","volume":"39","author":[{"given":"J.","family":"Powell","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Freeman Hospital Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Carding","sequence":"additional","affiliation":[{"name":"Speech Pathology Department Australian Catholic University Brisbane Qld Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Birdi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Freeman Hospital Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Freeman Hospital Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,7,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2001.117714"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1258\/00222150260369426"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.02.048"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812449108"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215107007177"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2000.00395.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215106005275"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20485"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21028"}],"container-title":["Clinical Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcoa.12274","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.12274","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T03:40:25Z","timestamp":1696390825000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/coa.12274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,16]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["10.1111\/coa.12274"],"URL":"https:\/\/doi.org\/10.1111\/coa.12274","archive":["Portico"],"relation":{},"ISSN":["1749-4478","1749-4486"],"issn-type":[{"value":"1749-4478","type":"print"},{"value":"1749-4486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,16]]}}}