{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:43:42Z","timestamp":1767919422326,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,3,14]],"date-time":"2016-03-14T00:00:00Z","timestamp":1457913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To study the correlation of obstructive sleep apnoea (<jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>) and laryngopharyngeal reflux (<jats:styled-content style=\"fixed-case\">LPR<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A descriptive study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Suez Canal University Hospital, Ismailia, Egypt.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients<\/jats:title><jats:p>62 patients with polysomnography confirmed <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Intervention<\/jats:title><jats:p>Patients were evaluated with ambulatory 24\u2010h double channel <jats:styled-content style=\"fixed-case\">pH<\/jats:styled-content> monitoring.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean reflux symptom index in the study group was 9 \u00b1 5.5, and it was &gt; 13 in all patients with severe <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>. Signs of <jats:styled-content style=\"fixed-case\">LPR<\/jats:styled-content> reflux were present in 34 (55%) patients. Abnormal reflux was detected in the distal oesophagus in 41 patients (66%) and in the proximal oesophagus in 21 patients (34%). Patients with severe <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> had significantly higher nocturnal <jats:styled-content style=\"fixed-case\">LPR<\/jats:styled-content> reflux episodes compared to patients with mild disease (<jats:italic>P<\/jats:italic> &lt; .05). Number of reflux episodes and total duration of reflux during sleep are significantly correlated to degree of <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> (<jats:italic>P<\/jats:italic> &lt; .05). No difference was found in relation to age or sex. Daytime reflux was not related to the degree of obstructive sleep apnoea (<jats:italic>P &gt;<\/jats:italic> .05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">LPR<\/jats:styled-content> is common in patients with <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>. Patients with severe <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> have significantly higher nocturnal <jats:styled-content style=\"fixed-case\">LPR<\/jats:styled-content>. 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