{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T22:39:15Z","timestamp":1779143955946,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T00:00:00Z","timestamp":1462320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Most previous studies have failed to show a relation between daytime sleepiness and apnoea severity in patients with obstructive sleep apnoea (<jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>). We determined the relation between daytime sleepiness and subjective and objective apnoea severity in newly diagnosed patients with moderate\u2010to\u2010severe <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective cross\u2010sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary referral centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>A total of 559 adults with newly diagnosed moderate and severe <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Daytime sleepiness was evaluated using the Epworth Sleepiness Scale (<jats:styled-content style=\"fixed-case\">ESS<\/jats:styled-content>). Subjective and objective apnoea severities were assessed using the Sleep Breathing Scale (<jats:styled-content style=\"fixed-case\">SBS<\/jats:styled-content>) and polysomnography respectively. Sleep quality and depressive symptoms were evaluated using Medical Outcomes Study\u2010Sleep Scale and Beck Depression Inventory (<jats:styled-content style=\"fixed-case\">BDI<\/jats:styled-content>) respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean <jats:styled-content style=\"fixed-case\">ESS<\/jats:styled-content> score was 9.8 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> 5.0). <jats:styled-content style=\"fixed-case\">ESS<\/jats:styled-content> score was correlated with <jats:styled-content style=\"fixed-case\">SBS<\/jats:styled-content> score (<jats:italic>P<\/jats:italic> &lt; 0.001), apnoea\u2212hypopnoea index (<jats:styled-content style=\"fixed-case\">AHI<\/jats:styled-content>) (<jats:italic>P<\/jats:italic> = 0.027), minimal oxygen saturation (MinSaO<jats:sub>2<\/jats:sub>) (<jats:italic>P<\/jats:italic> = 0.021), body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) (<jats:italic>P<\/jats:italic> = 0.007) and <jats:styled-content style=\"fixed-case\">BDI<\/jats:styled-content> score (<jats:italic>P<\/jats:italic> &lt; 0.001). Linear regression analysis showed that higher <jats:styled-content style=\"fixed-case\">SBS<\/jats:styled-content> (<jats:italic>P<\/jats:italic> = 0.005) and <jats:styled-content style=\"fixed-case\">BDI<\/jats:styled-content> scores (<jats:italic>P<\/jats:italic> &lt; 0.001) were associated with higher <jats:styled-content style=\"fixed-case\">ESS<\/jats:styled-content> score after controlling for gender, <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">AHI<\/jats:styled-content>. Apnoea\u2212hypopnoea index, MinSaO<jats:sub>2<\/jats:sub> and <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> were not independently related to <jats:styled-content style=\"fixed-case\">ESS<\/jats:styled-content> score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Daytime sleepiness was related to subjective <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> symptoms but not objective apnoea severity measured by polysomnography in patients with moderate\u2010to\u2010severe <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>. These findings suggest the usefulness of the subjective apnoea severity as an indicator of <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> disease severity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.12659","type":"journal-article","created":{"date-parts":[[2016,4,18]],"date-time":"2016-04-18T07:56:39Z","timestamp":1460966199000},"page":"395-401","source":"Crossref","is-referenced-by-count":13,"title":["Subjective apnoea symptoms are associated with daytime sleepiness in patients with moderate and severe obstructive sleep apnoea: a retrospective study"],"prefix":"10.1111","volume":"41","author":[{"given":"H.S.","family":"Ryu","sequence":"first","affiliation":[{"name":"Department of Neurology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.A.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.S.","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.S.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199304293281704"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2014.10.1.42"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-013-0851-2"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/pcad.1999.0410341"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/6.4.312"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.5.565"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-0035"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2008.02.006"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.2.9804051"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.120.6.1923"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-010-0343-6"},{"key":"e_1_2_7_13_1","first-page":"77","article-title":"A standardization study of Beck Depression Inventory I\u2010Korean version (K\u2010BDI): reliability and factor analysis","volume":"4","author":"Rhee H.M.","year":"1995","journal-title":"Korean J. 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