{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:10:43Z","timestamp":1767827443075,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T00:00:00Z","timestamp":1469491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to investigate the relationship between Bell's palsy and a novel oxidative stress parameter, thiol\/disulphide homeostasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A prospective study evaluating oxidative stress in Bell's palsy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>This research took place in the department of Otorhinolaryngology, Ataturk Training and Research Hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Totally, 77 patients with Bell's palsy and 38 healthy controls were included in this study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>The blood levels of total and native thiol and disulphide activity were assessed, and their levels were compared in the patients and controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were statistically significant differences between the patients and controls regarding thiol\/disulphide parameters. The mean native thiol and total thiol were significantly lower and disulphide levels were higher in the Bell's palsy than controls. On binary logistic regression analysis, the created model showed 45.3% variation. The cut\u2010off value was 18.95 for disulphides.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Native and total thiol levels were low in the Bell's palsy. This metabolic disturbance may have a role in the pathogenesis of Bell's palsy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.12701","type":"journal-article","created":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T16:51:02Z","timestamp":1467823862000},"page":"239-244","source":"Crossref","is-referenced-by-count":12,"title":["Thiol\/disulphide homeostasis in Bell's palsy as a novel pathogenetic marker"],"prefix":"10.1111","volume":"42","author":[{"given":"M.A.","family":"Babademez","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Y\u0131ld\u0131r\u0131m Beyaz\u0131t University School of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Gul","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Bitlis Tatvan State Hospital Bitlis Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Kale","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Ataturk Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Muderris","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Ataturk Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Bayazit","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Medipol University Faculty of Medicine Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ergin","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry Gaziantep 25 Aral\u0131k State Hospital Gaziantep Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Erel","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Head and Neck Surgery Y\u0131ld\u0131r\u0131m Beyaz\u0131t University School of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Kiris","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Y\u0131ld\u0131r\u0131m Beyaz\u0131t University School of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,7,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-124-1_Part_1-199601010-00005"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489109138433"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)91886-5"},{"key":"e_1_2_8_5_1","first-page":"83","article-title":"Protein oksidasyonunun ana mekanizmalar\u0131","volume":"35","author":"Kayal\u0131 R.","year":"2004","journal-title":"Cerrahpa\u015fa J. 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