{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T22:16:16Z","timestamp":1773526576919,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:00:00Z","timestamp":1490227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the risk of inflammation associated with fine\u2010needle aspiration during evaluation of Warthin's tumour.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary medical centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>All patients who underwent fine\u2010needle aspiration followed by parotidectomy between 1992 and 2009 for the diagnosis\/evaluation of a parotid gland tumour.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measure<\/jats:title><jats:p>Rate of fine\u2010needle\u2010aspiration\u2010related parotitis in patients with Warthin's tumour or other parotid pathologies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 593 parotidectomies were performed in 553 patients during the study period, 96 (16.2%) for Warthin's tumour (study group) and 497 for other parotid\u2010related pathologies (control group). Parotid gland inflammation following fine\u2010needle aspiration was observed in 16 cases in the study group (16.7%) and eight (1.6%) in the control group (<jats:italic>P<\/jats:italic>&lt;.001). On multivariate regression analysis, parotitis following fine\u2010needle aspiration was more common in patients with Warthin's tumour than other parotid\u2010related pathologies even after adjustment for possible confounders (<jats:italic>P<\/jats:italic>&lt;.007). Signs of inflammation were noted during surgery in six cases in the study group (6.3%) and none in the control group (<jats:italic>P<\/jats:italic>&lt;.001); respective rates of postoperative inflammation (wound infection) were 1.04% and 3.3% (<jats:italic>P<\/jats:italic>=<jats:styled-content style=\"fixed-case\">NS<\/jats:styled-content>). Management of parotitis consisted of hospitalisation and systemic antibiotic therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Warthin's tumour is associated with a tenfold higher risk of inflammation compared to other parotid tumours following invasive procedures. Clinicians should be alert to this complication in order to initiate proper treatment and patients must be properly counselled.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.12857","type":"journal-article","created":{"date-parts":[[2017,2,24]],"date-time":"2017-02-24T21:32:42Z","timestamp":1487971962000},"page":"1241-1246","source":"Crossref","is-referenced-by-count":10,"title":["Inflammation following invasive procedures for Warthin's tumour: A retrospective case series"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7957-5680","authenticated-orcid":false,"given":"U.","family":"Alkan","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2010 Head and Neck Surgery Rabin Medical Center \u2010 Beilinson Hospital Petach Tikva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Shkedy","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2010 Head and Neck Surgery Rabin Medical Center \u2010 Beilinson Hospital Petach Tikva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mizrachi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2010 Head and Neck Surgery Rabin Medical Center \u2010 Beilinson Hospital Petach Tikva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Shpitzer","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2010 Head and Neck Surgery Rabin Medical Center \u2010 Beilinson Hospital Petach Tikva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Popovtzer","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"},{"name":"Davidoff Cancer Center Rabin Medical Center \u2013 Beilinson Hospital Petach Tikva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Bachar","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2010 Head and Neck Surgery Rabin Medical Center \u2010 Beilinson Hospital Petach Tikva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890080309"},{"key":"e_1_2_8_3_1","first-page":"116","article-title":"Papillary cystadenoma lymphomatosum: a rare teratoid of the parotid region","volume":"13","author":"Warthin AS","year":"1929","journal-title":"J. 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